Setting a standard for a “silent” disease: defining osteoporosis in the 1980s and 1990s

Wylie, Caitlin Donahue

doi:10.1016/j.shpsc.2010.10.015

Cited by 16 publications

(18 citation statements)

References 35 publications

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“…A starting point for discussion is the current description of osteoporosis and how this has evolved. Medical dictionaries and reference books from 1972 to 1995 offered widely inconsistent definitions . Several attempts at international consensus failed but was eventually achieved at an international consensus conference held in Hong Kong in March 1993, sponsored by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, the European Foundation for Osteoporosis and Bone Disease (now the International Osteoporosis Foundation), and the American National Osteoporosis Foundation .…”

Section: Conceptual Definition Of Osteoporosismentioning

confidence: 99%

“…Medical dictionaries and reference books from 1972 to 1995 offered widely inconsistent definitions. (3) Several attempts at international consensus failed (4,5) but was eventually achieved at an international consensus conference held in Hong Kong in March 1993, sponsored by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, the European Foundation for Osteoporosis and Bone Disease (now the International Osteoporosis Foundation), and the American National Osteoporosis Foundation. (6) This landmark Consensus Development Conference described osteoporosis as: "A systemic skeletal disease characterized by low bone mass and micro-architectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture."…”

Section: Conceptual Definition Of Osteoporosismentioning

confidence: 99%

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Intervention Thresholds and the Diagnosis of Osteoporosis

Kanis

McCloskey

Harvey

et al. 2015

Journal of Bone and Mineral Research

110

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Section: Conceptual Definition Of Osteoporosismentioning

confidence: 99%

Section: Conceptual Definition Of Osteoporosismentioning

confidence: 99%

Intervention Thresholds and the Diagnosis of Osteoporosis

Kanis

McCloskey

Harvey

et al. 2015

Journal of Bone and Mineral Research

110

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“…Researchers, however, assigned different meanings to ‘osteoporosis’, with varying emphases on clinical, pathological physiological, and biochemical factors [3]. Medical dictionaries and reference books from 1972 to 1995 offer surprisingly inconsistent definitions [4]. Several attempts at international consensus failed [5, 6] but this was eventually successfully achieved at an international consensus conference organised by Claus Christiansen and John Kanis on the back of one of Claus’ osteoporosis meetings held in Hong Kong in March 1993, sponsored by the National Institute of Arthritis and Musculoskeletal and Skin Diseases, the European Foundation for Osteoporosis and Bone Disease and the American National Osteoporosis Foundation [7].…”

Section: Introductionmentioning

confidence: 99%

A brief history of FRAX

et al. 2018

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Summary This paper reviews the research programme that went into the development of FRAX® and its impact in the 10 years since its release in 2008. Introduction Osteoporosis is defined on the measurement of bone mineral density though the clinical consequence is fracture. The sensitivity of bone mineral density measurements for fracture prediction is low leading to the development of FRAX to better calculate the likelihood of fracture and target anti-osteoporosis treatments. Methods Literature review Results FRAX, developed over an eight-year period, was launched in 2008. Since the launch of FRAX, models have been made available for 64 countries and in 31 languages covering more than 80% of the world population. Conclusion FRAX provides an advance in fracture risk assessment and a reference technology platform for future improvements in performance characteristics.

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“…Primary osteoporosis (POP), also called “a silent disease,” is one of the pandemic public health issues that seriously threaten people's health all over the world [ 1 ]. Theoretically, POP and secondary osteoporosis belong to the field of osteoporosis (OP).…”

Section: Introductionmentioning

confidence: 99%

The Efficacy and Safety of Traditional Chinese Medicine Tonifying‐Shen (Kidney) Principle for Primary Osteoporosis: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Liang

Wang

Huang

et al. 2020

Evidence-Based Complementary and Alternative Medicine

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Objective. This study aimed to appraise the efficacy and safety of the tonifying-Shen (kidney) principle (TS (TK) principle) for primary osteoporosis (POP). Methods. Randomized controlled clinical trials (RCTs) using the TS (TK) principle for POP were searched from eight electronic databases to search for relevant literature that was published from the initiation to September 2019. Two reviewers performed study selection, data extraction, data synthesis, and quality assessment independently. Review Manager 5.3 software was used to assess the risk of bias and conduct the data synthesis. We assessed the quality of evidence for outcomes by using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system. Results. Thirty-six studies with 3617 participants were included. Meta-analysis showed a consistently superior effect of the TS (TK) principle combined with conventional Western medicine (CWM) in terms of total effectiveness rates (RR = 1.28; 95% CI (1.23, 1.33); P < 0.00001 ), BMD of the lumbar spine (SMD = 0.71; 95% CI (0.47, 0.95); P < 0.00001 ) and proximal femur (SMD = 0.94; 95% CI (0.49, 1.38); P < 0.00001 ), TCM symptom integral (SMD = −1.23; 95% CI (−1.43, −1.02); P < 0.00001 ), and VAS scores (SMD = −3.88; 95% CI (−5.29, −2.46); P < 0.00001 ), when compared to using CWM alone and with significant differences. Besides, in respect of adverse effects, it showed no significant statistical difference between the experimental and control groups, RR = 0.99 and 95% CI (0.65, 1.51), P = 0.97 . Conclusion. Our meta-analysis provides promising evidence to suggest that using the TS (TK) principle combined with CWM for POP is more effective than using CWM alone. Also, both of them are safe and reliable for POP.

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Setting a standard for a “silent” disease: defining osteoporosis in the 1980s and 1990s

Cited by 16 publications

References 35 publications

Intervention Thresholds and the Diagnosis of Osteoporosis

Intervention Thresholds and the Diagnosis of Osteoporosis

A brief history of FRAX

The Efficacy and Safety of Traditional Chinese Medicine Tonifying‐Shen (Kidney) Principle for Primary Osteoporosis: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

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