2000
DOI: 10.1177/03008916000864s105 View full text |Buy / Rent full text
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Abstract: Background: Osteosarcoma accounts for 60% of all malignant childhood bone tumors. Standard treatment traditionally involved limb amputation at the joint proximal to the affected bone. Limb salvage procedures now offer therapeutic alternatives. Moreover adjuvant and postoperative chemotherapy can reduce micrometastases and tumor size. Nevertheless, 40% of all osteosarcoma patients experience relapse within .s ye:irs. and 30% of relapsing patients develop lung metastasis withm the first year. The obstinate cours… Show more

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