Sesamin a potent antifeedant principle fromPiper mullesua

Srivastava, Sangeeta; Gupta, Madan M.; Prajapati, Veena; Tripathi, Arun Kumar; Kumar, Sushil

doi:10.1002/1099-1573(200102)15:1<70::aid-ptr671>3.0.co;2-n

Cited by 25 publications

(13 citation statements)

References 11 publications

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“…Eudesmin ( 2 ) and sesamin ( 3 ) are structurally related. Sesamin is known for its growth‐inhibition against Bombyx mori (L) and antifeedant activity against Spilarctia obliqua (Walker) larvae,14, 15 and was found to be synergistic to several synthetic insecticides 14…”

Section: Introductionmentioning

confidence: 99%

Insecticidal activity of chemical constituents from Aristolochia pubescens against Anticarsia gemmatalis larvae

Nascimento¹,

Murata²,

Bortoli³

et al. 2003

Pest Management Science

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Acetone and ethanol extracts of the tubercula and several compounds isolated from Aristolochia pubescens (Willd) were bioassayed on velvetbean caterpillars, Anticarsia gemmatalis (Hübner), for evaluation of the insecticidal activities. Of the extracts subjected to bioassay, the acetone extract showed the highest activity. (-)-Cubebin did not show activity against soybean caterpillars, whereas aristolochic acid and ent-kaur-15-en-17-ol increased the larval period. These compounds, and (+)-eudesmin and (+)-sesamin, reduced the viability of this period, giving rise to malformed adults. These extracts and compounds are therefore potential botanical insecticide agents for the control of velvetbean caterpillars in soybean crops.

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Section: Introductionmentioning

confidence: 99%

Insecticidal activity of chemical constituents from Aristolochia pubescens against Anticarsia gemmatalis larvae

Nascimento¹,

Murata²,

Bortoli³

et al. 2003

Pest Management Science

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“…As for lignans, the feeding deterrent activities of two sesamin-type compounds (1 and 2) were generally poor. However, sesamin was reported to exhibit significant antifeedant activity towards Spilarctia obliqua larvae, and it was considered as a potent antifeedant principle from Piper mullesua [43]. Additionally, a piece of old literature mentioned that sesamin-type lignans could function as active insecticidal synergists for pyrethrins and rotenone without increasing toxicity to mammals [44].…”

Section: Feeding Deterrent Activity Results Inmentioning

confidence: 99%

Repellent and Feeding Deterrent Activities of Butanolides and Lignans Isolated fromCinnamomum camphoraagainstTribolium castaneum

Wang

Zhang

et al. 2020

Journal of Chemistry

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Three lignans (1–3) and three butanolides (4–6) were isolated from the lipophilic extract of the Cinnamomum camphora stem bark. The six compounds were identified as (-)-sesamin (1), 9α-hydroxysesamin (2), 9β-hydroxysesamin (3), obtusilactone A (4), isoobtusilactone A (IOA, 5), and isomahubanolide (6) from their spectroscopic data. Four (1, 2 and 5, 6) of them were evaluated for their repellent and feeding deterrent activities against Tribolium castaneum. In this work, the three butanolides (4–6) were confirmed to exist in C. camphora for the first time. Results of bioassays indicated that (-)-sesamin (1), IOA (5), and isomahubanolide (6) displayed certain repellent activities against T. castaneum at 78.63, 15.73, and 3.15 μg/cm2 at 2 h after exposure. Among the three compounds, (-)-sesamin (1) and IOA (5) exerted stronger effects and maintained longer duration of repellency. Furthermore, IOA (5) and isomahubanolide (6) showed good feeding deterrent activity against T. castaneum. IOA (5) was still potently active at low concentrations with the feeding deterrence index (FDI) ranging from 42.85% to 50.66% at 15–1500 ppm. This work provides some evidence for explaining antiinsect properties of the nonvolatile fraction of the C. camphora stem bark and helps promote the development and comprehensive utilization of this tree species.

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“…The isoquinoline moiety could be the pharmacophore of this class of compounds and the presence of a ketone at C-7, C-4 or C-5 [22] seems to contribute to the activity. Sesamin, which showed moderated larvicidal activity, has also been reported to have antifeeding and growth-inhibition activities [23]. …”

Section: Resultsmentioning

confidence: 99%

Zanthoxoaporphines A–C: Three new larvicidal dibenzo[de,g]quinolin-7-one alkaloids from Zanthoxylum paracanthum (Rutaceae)

Samita¹,

Sandjo²,

Ndiege³

et al. 2013

Beilstein J. Org. Chem.

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SummaryThe bioassay-guided purification of Zanthoxylum paracanthum (Rutaceae) extracts led to the isolation of three new alkaloids, namely 1-hydroxy-10-methoxy-7H-dibenzo[de,g]quinolin-7-one (zanthoxoaporphine A, 2), 1-hydroxy-7H-dibenzo[de,g]quinolin-7-one (zanthoxoaporphine B, 3) and 1,8-dihydroxy-9-methoxy-7H-dibenzo[de,g]quinolin-7-one (zanthoxaporphine C, 4), and a known lignan identified as sesamin (1). Isolation and purification of the constituent compounds was achieved through conventional chromatographic methods. The chemical structures of the isolated compounds were determined on the basis of UV, IR, NMR and MS data, and confirmed by comparison with those reported in the literature. The larvicidal activity of some of the isolated compounds was investigated by using third-instar Anopheles gambiae larvae.

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Sesamin a potent antifeedant principle fromPiper mullesua

Cited by 25 publications

References 11 publications

Insecticidal activity of chemical constituents from Aristolochia pubescens against Anticarsia gemmatalis larvae

Insecticidal activity of chemical constituents from Aristolochia pubescens against Anticarsia gemmatalis larvae

Repellent and Feeding Deterrent Activities of Butanolides and Lignans Isolated fromCinnamomum camphoraagainstTribolium castaneum

Zanthoxoaporphines A–C: Three new larvicidal dibenzo[de,g]quinolin-7-one alkaloids from Zanthoxylum paracanthum (Rutaceae)

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