Serum vitamin D and vitamin D receptor gene FokI polymorphisms in children with tuberculosis

Abstract

Background Vitamin D deficiency and vitamin D receptor (VDR)

The association between vitamin D status and tuberculosis in children

“…The included studies were published between 2012 and 2017. Four studies [20–23] described the difference in 25(OH)D levels in children with TB and controls; two [21,23] of these studies calculated 25(OH)D levels in nmol/L, and two [20,22] calculated 25(OH)D levels in ng/mL. Four studies [24–27] evaluated the association between the presence of any TB and VDD.…”

“…One study [25] showed a significant association between the presence of any TB and VDD, while 2 studies [24,25] showed a significant association between the presence of active TB and VDD; however, 3 studies [24,26,27] showed a nonsignificant association between the presence of any TB and VDD. Four studies [22,23,28,29] showed that VDD contributes to TB.…”