Serum galectin-3 levels in women with PCOS

Abstract

Galectin-3 levels are higher in patients with PCOS, and there is a positive correlation between galectin-3 level and IR, androgen levels and hirsutismus scores. Gal-3 may be a new mediator of PCOS via IR, hyperandrogenism.

Increased levels of galectin-3 were associated with prediabetes and diabetes: new risk factor?

“…However, these patients were previously known to have diabetes. In a study performed by our group, we reported the correlation of galectin-3 levels with insulin resistance in patients with polycystic ovary syndrome [16]. Until now, the effect of Gal-3 on the development of prediabetes and T2DM has remained unclear.…”

“…Impaired glucose tolerance (IGT) is defined as 2hPG values in the 75-g OGTT of 140 to 199 mg/dL [14]. IFG, IGT, or both of these conditions are accepted as prediabetes [16]. We used the following two criteria for the diagnosis of diabetes: FPG ≥126 mg/dL and 2hPG ≥200 mg/dL [16].…”

“…IFG, IGT, or both of these conditions are accepted as prediabetes [16]. We used the following two criteria for the diagnosis of diabetes: FPG ≥126 mg/dL and 2hPG ≥200 mg/dL [16]. This cross-sectional study was approved by the Ethics Committee of Turgut Ozal University.…”

“…We recently demonstrated that galectin-3 correlates positively with insulin resistance in women with polycystic ovary syndrome [16].…”

Serum galectin‐3 concentrations in patients with ankylosing spondylitis

“…Galectin‐3 is a member of soluble β‐galactoside‐binding lectin, which plays an important role in the development of inflammation and fibrosis . Previous studies have shown that increased galectin‐3 expression was observed in various cancer cells .…”