Seroprevalencia de la infección por el virus herpes simplex tipo 2 en tres grupos poblacionales de la Ciudad de México

Conde-González, Carlos J; Lazcano‐Ponce, Eduardo; Hernández–Girón, Carlos; Juárez-Figueroa, Luis; Smith, Jennifer S.; Hernández-Ávila, Mauricio

doi:10.1590/s0036-36342003001100005

Cited by 3 publications

(1 citation statement)

References 19 publications

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“…Herpes is an emerging disease, caused by infection and replication of HSV-1 and HSV-2 in in mucosal tissue cells, both in the mouth and genitals. This disease is characterized by the appearance of erythematous vesicles that tend to quickly erode causing painful ulcers, accompanied by various clinical manifestations that can range from fever, malaise, diffuse muscle pain, headaches, itching and symptoms depend on the affected area [1][2][3]. HSV-1 and HSV-2 belong to the alpha subfamily of the Herpesvirus (or Herpesviridae) family, which includes a relatively large number of viruses with DNA genetic material.…”

Section: Herpes Simplex Virusmentioning

confidence: 99%

Antiherpetic Plants: A Review of Active Extracts, Isolated Compounds, and Bioassays

Silva-Mares

Torres‐López

Rivas-Galindo

2016

Natural Product Communications

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Herpes simplex is a disease that is widely distributed throughout the world. It is caused by herpes simplex virus type 1 (HSV-1) and simplex virus type 2 (HSV-2). The drugs of choice for treatment are acyclovir (ACV), Penciclovir (PCV) and other guanine analogues, which have the same mechanism of action. However, due to the constant increase of ACV-resistant strains in immunocompromised patients, it is necessary to find new treatment alternatives. It has been shown that natural products are a good alternative for the treatment of these diseases as well as being an excellent source of compounds with anti-herpetic activity, which may be useful for the development of new drugs and act through a mechanism of action different from ACV and PCV. This paper compiles reports on extracts and compounds isolated from plants that have anti-herpetic activity. We present an analysis of the solvents most widely used for extraction from plants as well as cells and commonly used methods for evaluating cytotoxic and anti-herpetic activity. Families that have a higher number of plants with anti-herpetic activity are evaluated, and we also highlight the importance of studies of mechanisms of action of extracts and compounds with anti-herpetic activity.

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Section: Herpes Simplex Virusmentioning

confidence: 99%

Antiherpetic Plants: A Review of Active Extracts, Isolated Compounds, and Bioassays

Silva-Mares

Torres‐López

Rivas-Galindo

2016

Natural Product Communications

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Prevalence of active infection by herpes simplex virus type 2 in patients with high‐risk human papillomavirus infection: A cross‐sectional study

Bahena-Román

Sánchez‐Alemán

Contreras‐Ochoa

et al. 2020

Journal of Medical Virology

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The aim is to determine the prevalence of active infection by herpes simplex virus type 2 (HSV‐2) among Mexican women with high‐risk human papillomavirus (HR‐HPV) cervical infection, recruited from public gynecology and colposcopy services. In a cross‐sectional study, HSV‐2 antibodies, HSV‐2 DNA, and HR‐HPV DNA were quantified. Significant differences in HSV‐2 seroprevalence and HSV‐2 active infection rates were found between negative and positive HR‐HPV cases. HSV‐2 seroprevalence was 28.15% and 16.1% (P = .0001), while HSV‐2 active infection rates were 6.83% and 0.62% (P = .001) for positive and negative HR‐HPV groups, respectively. The risk of HSV‐2 seropositivity was 1.7 times greater for HR‐HPV‐positive cases (P = .02). Similarly, HR‐HPV‐positive cases were nine times more likely to have an HSV‐2 active infection than HR‐HPV‐negative cases (P = .03). High HSV‐2/h‐HPV coinfection rates were observed among women recruited from public gynecology and colposcopy services. The main factors related to an HSV‐2 active infection are a history of risky sexual behavior and HR‐HPV infection. The prevalence of HSV‐2 active infection among positive HR‐HPV subjects indicate that these infections constitute an important group of STIs in Mexico.

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Risk behaviors of 15–21 year olds in Mexico lead to a high prevalence of sexually transmitted infections: results of a survey in disadvantaged urban areas

et al. 2006

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Seroprevalencia de la infección por el virus herpes simplex tipo 2 en tres grupos poblacionales de la Ciudad de México

Cited by 3 publications

References 19 publications

Antiherpetic Plants: A Review of Active Extracts, Isolated Compounds, and Bioassays

Antiherpetic Plants: A Review of Active Extracts, Isolated Compounds, and Bioassays

Prevalence of active infection by herpes simplex virus type 2 in patients with high‐risk human papillomavirus infection: A cross‐sectional study

Risk behaviors of 15–21 year olds in Mexico lead to a high prevalence of sexually transmitted infections: results of a survey in disadvantaged urban areas

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