Seroprevalence of Trypanosoma cruzi infection in blood donors in the extreme South of Brazil

Bianchi, Tanise Freitas; Grala, Ana Paula da Paz; Leon, Ítalo Ferreira De; Jeske, Sabrina; Pinto, Gisele Ortiz Heidrich; Villela, Marcos Marreiro

doi:10.1590/0037-8682-0599-2021

Cited by 3 publications

(1 citation statement)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Recent data on human seroprevalence of T. cruzi in RS have shown positivity rates between 0.27% and 5% in studies carried out with residents in southern RS 10 - 12 . It shows an important prevalence of CD among this population, since the disease’s main prevalence among blood donors in Brazil was 0.21% 12 . T. rubrovaria remains the epidemiologically most disperse and relevant species in RS 13 .…”

Section: Introductionmentioning

confidence: 99%

Triatoma rubrovaria (Hemiptera, Reduviidae, Triatominae) in the Pampa biome, Brazil: a retrospective study of its occurrence and abundance

Souza,

Santos,

Bedin

et al. 2023

Rev. Inst. Med. trop. S. Paulo

Self Cite

View full text Add to dashboard Cite

Triatoma rubrovaria has been captured in some areas of Rio Grande do Sul State (RS), Brazil, as this species can be found in the Pampa biome. Its distribution across this biome should be described in detail to verify the potential of this vector to transmit Trypanosoma cruzi . This study aimed to investigate the occurrence of T. rubrovaria in the Pampa biome and transitional areas of RS. The collected information resulted from the analysis of secondary data provided by the Centro Estadual de Vigilancia em Saude (CEVS – State’s Center of Health Surveillance). The following aspects were taken into consideration: the year in which the insect was captured, the city, the number of specimens captured, invasion or domiciliation, the notification in the household, surroundings or both, and T. cruzi infection. The data comprised the period from 2009 to 2020, in 109 cities located in the Pampa biome and 98 located in transitional areas. The Pampa biome exhibited 85% of the occurrences of T. rubrovaria, while 1.2% of specimens were T. cruzi- like positive. Both the first and second biennia concentrated 64.6% of captures. Alegrete city, Cangucu city and Piratini city were the locations in the Pampa where the largest numbers of specimens were found. Regarding the transitional areas, Roque Gonzales city, Santiago city and Santana da Boa Vista city exhibited the largest numbers. Most insects were adults, which were found in households. Even though positivity for T. cruzi -like was low, the species still has epidemiological importance in the region.

show abstract

Section: Introductionmentioning

confidence: 99%

Triatoma rubrovaria (Hemiptera, Reduviidae, Triatominae) in the Pampa biome, Brazil: a retrospective study of its occurrence and abundance

Souza,

Santos,

Bedin

et al. 2023

Rev. Inst. Med. trop. S. Paulo

Self Cite

View full text Add to dashboard Cite

show abstract

Difficultés d’interprétation des sérologies parasitaires, hors toxoplasmose

Houzé

Paris²

2022

Revue Francophone des Laboratoires

View full text Add to dashboard Cite

Outcomes of kidney transplant recipients exposed to Chagas disease under Benznidazole prophylaxis. A single center 10‐year experience

Budel,

Alegretti,

Prado

et al. 2024

Transplant Infectious Dis

View full text Add to dashboard Cite

BackgroundChagas disease (ChD) is endemic in many parts of the world and can be transmitted through organ transplantation or reactivated by immunosuppression. Organs from infected donors are occasionally used for transplantation, and the best way of managing the recipients remains a subject of debate.MethodsWe present a single‐center cohort study describing a 10‐year experience of kidney transplantation in patients at risk of donor‐derived ChD and or reactivation. Patients received prophylactic treatment with Benznidazole and were monitored for transmission or reactivation. Monitoring included assessing direct parasitemia, serology, and polymerase chain reaction (PCR).ResultsFifty‐seven kidney transplant recipients (KTRs) were enrolled in the study. Forty‐four patients (77.2%) were at risk of primary ChD infection, nine patients (15.8%) were at risk of disease reactivation, and four patients (7.0%) were at risk of both. All patients received Benznidazole prophylaxis, starting on the first day after transplantation. Parasitemia was assessed in 51 patients (89.5%), serology also in 51 patients (89.5%), and PCR in 40 patients (70.2%). None of the patients exhibited clinically or laboratory‐detectable signs of disease. A single patient experienced a significant side effect, a cutaneous rash with intense pruritus. At 1‐year post‐transplantation, the patient and graft survival rates were 96.5% and 93%, respectively.ConclusionIn this study, no donor‐derived or reactivation of Trypanosoma cruzi infection occurred in KTRs receiving Benznidazole prophylaxis.

show abstract

Seroprevalence of Trypanosoma cruzi infection in blood donors in the extreme South of Brazil

Abstract: Background:We aimed to evaluate the seroprevalence of Chagas disease among blood donors in southern Rio Grande do Sul, Brazil.

Cited by 3 publications

References 9 publications

Triatoma rubrovaria (Hemiptera, Reduviidae, Triatominae) in the Pampa biome, Brazil: a retrospective study of its occurrence and abundance

Triatoma rubrovaria (Hemiptera, Reduviidae, Triatominae) in the Pampa biome, Brazil: a retrospective study of its occurrence and abundance

Difficultés d’interprétation des sérologies parasitaires, hors toxoplasmose

Outcomes of kidney transplant recipients exposed to Chagas disease under Benznidazole prophylaxis. A single center 10‐year experience

Contact Info

Product

Resources

About