Seroprevalence of SARS-CoV-2 antibodies in low-income university students

Araújo, Adriano Antunes de Souza; Quintans‐Júnior, Lucindo José; Schimieguel, Dulce Marta; Corrêa, Cristiane Bani; Moura, Tatiana Rodrigues de; Cavalcante, Rafael Ciro Marques; Grespan, Renata; Cerqueira-Meneses, Daniele de Vasconcelos; Barreto-Alves, José Antônio; Martins-Filho, Paulo Ricardo

doi:10.17179/excli2021-3459

Cited by 3 publications

(1 citation statement)

References 5 publications

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“…To our knowledge, few studies have reported the seroprevalence of SARS-CoV-2 infection in universities [ 5 , 6 , 7 , 8 , 9 ]. In the current context, and given the current lack of knowledge in this field, we decided to set up a cross-sectional study to estimate the seroprevalence of SARS-CoV-2 within the staff and student populations of the University of Corsica (France), as well as the exposure factors and symptoms related to seropositivity during the second COVID-19 epidemic wave.…”

Section: Introductionmentioning

confidence: 99%

A Cross-Sectional Study of Exposure Factors Associated with Seropositivity for SARS-CoV-2 Antibodies during the Second Epidemic Wave among a Sample of the University of Corsica (France)

Decarreaux

Sevila

Masse

et al. 2022

IJERPH

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This study aimed to estimate the seroprevalence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection within the staff and student populations of the University of Corsica (France) during the second wave of the epidemic. Methods: A cross-sectional survey was conducted from 23 November 2020 to 31 January 2021. The participants underwent blood sampling using a fingerstick procedure and completed an anonymized questionnaire. Sera were tested for the presence of anti-SARS-CoV-2 IgG (ELISA-S) and, if positive, with an in-house virus neutralization test (VNT). Results: A total of 418 persons were included in the study. The overall seroprevalence was 12.8% (95% confidence interval (CI), 9.8–16.6%). A total of 15 (31%) of the 49 individuals who had a positive ELISA-S also had a positive VNT. Seropositivity was associated with living at the city campus during the week and on weekends (OR = 3.74 [1.40–12.00]), using public transportation/carpooling (OR = 2.00 [1.01–4.02]), and being in contact with a person who tested positive for SARS-CoV-2 (OR = 2.32 [1.20–4.40]). The main symptoms associated with seropositivity were “having had an acute respiratory infection” (OR = 3.05 [1.43–6.43]) and “experiencing loss of smell” (OR = 16.4 [5.87–50.7]). Conclusion: These results could be useful for SARS-CoV-2 prevention and control on university campuses.

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Section: Introductionmentioning

confidence: 99%

A Cross-Sectional Study of Exposure Factors Associated with Seropositivity for SARS-CoV-2 Antibodies during the Second Epidemic Wave among a Sample of the University of Corsica (France)

Decarreaux

Sevila

Masse

et al. 2022

IJERPH

View full text Add to dashboard Cite

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Seroprevalence of SARS-CoV-2 in Brazil: A systematic review and meta-analysis

Figueiredo

Tengan

Campos

et al. 2023

Clinics

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Seroprevalence of SARS-CoV-2 Antibodies and Factors Associated with Seropositivity at the University of Salamanca: The DIANCUSAL Study

Muro

Belhassen‐García

Bellido

et al. 2021

JCM

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Background: Systematic screening for antibodies against SARS-CoV-2 is a crucial tool for surveillance of the COVID-19 pandemic. The University of Salamanca (USAL) in Spain designed a project called “DIANCUSAL” (Diagnosis of New Coronavirus, COVID-19, in University of Salamanca) to measure antibodies against SARS-CoV-2 among its ~34,000 students and academic staff, as the influence of the university community in the spread of the SARS-CoV-2 pandemic in the city of Salamanca and neighboring towns hosting USAL campuses could be substantial. Objective: The aim of this study was to estimate the prevalence of SARS-CoV-2 antibodies among USAL students, professors and staff and to evaluate the demographic, academic, clinical and lifestyle and behavioral factors related to seropositivity. Methodology: The DIANCUSAL study is an ongoing university population-based cross-sectional study, with the work described herein conducted from July–October 2020. All USAL students, professors and staff were invited to complete an anonymized questionnaire. Seroprevalence of anti-SARS-CoV-2 antibodies was detected and quantified by using chemiluminescent assays for IgG and IgM. Principal findings: A total of 8197 (24.71%) participants were included. The mean age was 31.4 (14.5 SD) years, and 66.0% of the participants were female. The seroprevalence was 8.25% overall and was highest for students from the education campus (12.5%) and professors from the biomedical campus (12.6%), with significant differences among faculties (p = 0.006). Based on the questionnaire, loss of smell and fever were the symptoms most strongly associated with seropositivity, and 22.6% of seropositive participants were asymptomatic. Social distancing was the most effective hygiene measure (p = 0.0007). There were significant differences in seroprevalence between participants with and without household exposure to SARS-CoV-2 (p = 0.0000), but not between students who lived in private homes and those who lived in dormitories. IgG antibodies decreased over time in the participants with confirmed self-reported COVID-19 diagnoses. Conclusions: The analysis revealed an overall 8.25% seroprevalence at the end of October 2020, with a higher seroprevalence in students than in staff. Thus, there is no need for tailored measures for the USAL community as the official average seroprevalence in the area was similar (7.8% at 22 June and 12.4 at 15 November of 2020). Instead, USAL members should comply with public health measures.

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Seroprevalence of SARS-CoV-2 antibodies in low-income university students

Cited by 3 publications

References 5 publications

A Cross-Sectional Study of Exposure Factors Associated with Seropositivity for SARS-CoV-2 Antibodies during the Second Epidemic Wave among a Sample of the University of Corsica (France)

A Cross-Sectional Study of Exposure Factors Associated with Seropositivity for SARS-CoV-2 Antibodies during the Second Epidemic Wave among a Sample of the University of Corsica (France)

Seroprevalence of SARS-CoV-2 in Brazil: A systematic review and meta-analysis

Seroprevalence of SARS-CoV-2 Antibodies and Factors Associated with Seropositivity at the University of Salamanca: The DIANCUSAL Study

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