Seroprevalence of Neospora caninum in dogs from greater Sydney, Australia unchanged from 1997 to 2019 and worldwide review of adult-onset of canine neosporosis

Barker, Andrew; Wigney, D. I.; Child, Georgina; Šlapeta, Jan

doi:10.1016/j.crpvbd.2020.100005

Cited by 7 publications

(9 citation statements)

References 49 publications

(75 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This report contains two cases of clinical lumbosacral neosporosis, with case 1 representing the more typical age for this presentation (<6 months) and case 2 demonstrating a more atypical presentation for neosporosis in an older dog, where encephalitis/cerebellitis is more commonly reported. [6][7][8][9] The MRI findings concerning lumbosacral multifocal myositis, multifocal radiculoneuritis, focal meningitis and focal myelitis associated with N. caninum infection have not yet been reported. To date, the published data concentrate primarily on multifocal meningoencephalitis, 8 necrotising cerebellitis 6,7 and cervical myelitis/myositis.…”

Section: Discussionmentioning

confidence: 99%

“…A study performing end titration of serum from healthy dogs that tested positive at 1:50 for anti-N. caninum IgG antibodies discovered that twothirds (18/27) remained positive at 1:800 and one-third (9/27) remained positive at 1:3200. 9 It has been recommended that a rising serological antibody would be a more appropriate diagnostic tool, although this does potentially delay the time of diagnosis. 15 PCR affords the opportunity to directly identify the presence of the pathogen at affected sites; however, to the authors' knowledge, the sensitivity of PCR on any tissue for N. caninum has not been directly evaluated in dogs.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Lumbosacral MRI findings in two dogs diagnosed with a Neospora caninum infection

Clark

Shaw

Sánchez

2022

Vet Record Case Reports

View full text Add to dashboard Cite

A 5‐month‐old, male, entire labrador retriever (case 1) and a 6‐year‐old, female, neutered greyhound (case 2) presented following chronic, progressive, non‐painful paraparesis in both cases with L4–Cd and L4–S1 neurolocalisation respectively. Magnetic resonance imaging of the lumbosacral region revealed multifocal muscular changes in both cases with patchy T2‐weighted and water‐weighted T2‐weighted Dixon hyperintensities, with moderate contrast enhancement throughout the gluteal and lumbar paraspinal muscles. Multifocal radiculoneuropathy in case 1 and meningomyelitis in case 2 were identified. Crucially, in case 1, the identification of abnormal muscles on magnetic resonance imaging allowed the diagnosis of neosporosis via polymerase chain reaction on targeted muscle biopsy when previously indirect fluorescent antibody test serology was inconclusive and polymerase chain reaction on lumbar cerebrospinal fluid was negative. These cases highlight the magnetic resonance imaging findings of canine lumbar neosporosis and offer an alternative route of diagnosis through targeted muscle biopsy.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Lumbosacral MRI findings in two dogs diagnosed with a Neospora caninum infection

Clark

Shaw

Sánchez

2022

Vet Record Case Reports

View full text Add to dashboard Cite

show abstract

“…The positive titer result for Neospora caninum was not reported until after the diagnosis ACH had been made by PCR (see below). This was assumed to be clinically insignificant ( 13 , 14 ).…”

Section: Case Descriptions and Diagnostic Assessmentmentioning

confidence: 99%

American Canine Hepatozoonosis Causes Multifocal Periosteal Proliferation on CT: A Case Report of 4 Dogs

et al. 2022

View full text Add to dashboard Cite

American canine hepatozoonosis (ACH) represents an important but relatively uncommon differential diagnosis in a dog with fever, muscle wasting, profound leukocytosis, and/or musculoskeletal pain. Despite this, obtaining a definitive diagnosis can prove difficult. Peripheral blood smears and whole-blood polymerase chain reaction (PCR) rely on rare parasitemia, and the gold standard diagnostic test (skeletal muscle biopsy) is uncommonly pursued due to its invasive and costly nature. Demonstration of characteristic periosteal proliferative lesions aids diagnosis. The lesions typically involve the more proximal long bones of the appendicular skeleton. The periosteal proliferation is of currently unknown pathogenesis, but its distribution is characteristic of this disease with few differential diagnoses. This case series describes the findings on computed tomography (CT) in 4 dogs with PCR- or cytologically-confirmed Hepatozoon americanum. All dogs had multifocal, bilaterally asymmetric, irregularly marginated, non-destructive, non-articular, periosteal proliferative lesions. Recognition of this unusual CT finding and awareness of this disease could assist in the diagnosis and subsequent treatment of dogs with ACH and may offer an additional indication for CT in cases of fever, muscle wasting, and myalgia.

show abstract

“…(2021) and Wu-Chuang et al. (2021) , and the primary research papers by Barker et al. (2021) , Egan et al.…”

mentioning

confidence: 99%

Editorial: First anniversary of

Kostadinova

2021

Current Research in Parasitology & Vector-Borne Diseases

View full text Add to dashboard Cite

Seroprevalence of Neospora caninum in dogs from greater Sydney, Australia unchanged from 1997 to 2019 and worldwide review of adult-onset of canine neosporosis

Cited by 7 publications

References 49 publications

Lumbosacral MRI findings in two dogs diagnosed with a Neospora caninum infection

Lumbosacral MRI findings in two dogs diagnosed with a Neospora caninum infection

American Canine Hepatozoonosis Causes Multifocal Periosteal Proliferation on CT: A Case Report of 4 Dogs

Editorial: First anniversary of

Contact Info

Product

Resources

About