Breast cancer is the most common invasive cancer and the second leading cause of cancer death in females after lung cancer (Bray et al., 2018). Only in 2018, 2,088,849 and 626,679 new cancer cases and related death, respectively, occurred in worldwide (Bray et al., 2018). Histologically, most of breast cancer cases start from milk ducts and called ductal carcinoma. The second most frequent type of breast cancer, lobular carcinoma, begins in the milk-producing glands of the breast that is histologic forms of this malignancy (Li et al., 2005;Sharma et al., 2010). Less-common other types of breast cancer include tubular, mucinous, comedo, and medullary type (Li et al., 2005). Tumor grades include types I, II and III, which are used to describe the rate of growth and