Seroprevalence and epidemiology of Helicobacter pylori infection in patients with cirrhosis

Role of Helicobacter pylori infection in the pathogenesis of minimal hepatic encephalopathy and effect of its eradication

“…The role of H. pylori in the pathogenesis of hyperammonemia has been shown in previous studies which showed a reduction in blood ammonia levels after eradication of H. pylori infection [6,13]. However, some other studies have failed to show an association between H. pylori infection and hepatic encephalopathy [14][15][16].…”

Helicobacter pylori promotes hepatic fibrosis in the animal model

“…3,5 Moreover, the prevalence of H. pylori in patients with cirrhosis has been reported to be remarkably higher than in non-cirrhotic patients. 6,7 Helicobacter-like DNA that showed a high similarity to H. pylori and enterohepatic Helicobacter species was detected in the liver by PCR. 8,9 Taken together, these observations support the idea that H. pylori infection may have a critical role in the pathogenesis of various liver disorders.…”

Helicobacter pylori: Effect of coexisting diseases and update on treatment regimens

“…A group of researchers from Taiwan found that 21 (58%) patients in whom H. pylori infections were eradicated developed recurrent duodenal ulcers within a year [60] . These results suggest that the pathogenesis of ulcer disease in a substantial proportion of patients with cirrhosis may not be related to H. pylori infection, a possibility proposed by researchers [65,67] . However, early H. pylori eradication is associated with a lower risk of recurrent peptic ulcers in cirrhotic patients, according to a Taiwan populationbased study [77] .…”

“…The prevalence of H. pylori in patients with cirrhosis and PUD is generally less than 60% [60,[62][63][64][65] , suggesting that the pathogenesis of ulcer disease in a substantial proportion of cirrhotic patients may not be related to H. pylori infection [66][67][68][69] . Host environments are crucial to H. pylori colonization [7,70] .…”