Seropositivity diagnosis for hantavirus in Jataí, Goiás State, Brazil

Abstract

Introduction: Emerging diseases are of great interest, especially those associated with high mortality rates such as hantaviruses. We aimed to conduct a seroepidemiological survey to determine the levels of hantavirus infection. Methods: In-house enzyme-linked immunosorbent assay (ELISA) was used to detect specific antibodies. Results: Of the 429 samples collected, seropositivity of 3.9% to anti-hantavirus immunoglobulin G (IgG) was observed (CI 95%: 2.3-5.7). Moreover, in three cases, immunoglobulin M (IgM) was detected, of which two were diagnosed as hantavirus cardiopulmonary syndrome (HCPS). Conclusions: Our data indicate the considerable occurrence of previous hantavirus infections, highlighting occurrences from sub-clinical cases to HCPS.

Rodent-borne viruses survey in rural settlers from Central Brazil

“… 16 The prevalence of anti-hantavirus IgG antibodies detected in this study is in accordance with prevalence found in different studies conducted in rural populations from Brazil (0.4% to 22.0%), 17 , 18 , 19 , 20 , 21 , 22 , 23 but is lower than the one found for Jataí municipality 3.9% (95% CI: 2.3-5.7). 24 According to Guzmán et al, 11 this difference could be explained by the lower sensitivity found in the serological testes using Maciel orthohantavirus when compared to those obtained using Araraquara orthohantavirus. Studies also show considerable serological prevalence for hantavirus in men, that seem to link hantavirus infection and field related activities.…”