Seronegative conversion of an HIV positive subject treated with <i>Nigella sativa</i> and honey

Abstract

Background: There are many documented roles of Nigella sativa and honey in treatment of diseases but the least expected are the potentials in curing HIV infection. Materials and Method: A 27 years old HIV infected woman was diagnosed during antenatal care (ANC) at General Hospital (EIA) and confirmed with Western blot in 2004 at National Institute of Medical Research, Lagos (NIMR). She could not benefit from free antiretroviral therapy because her CD4 count was above 200 cells/ µL (350 cells/ µL) thus herbal therapist commenced her on Nigella sativa and honey therapy (60: 40 respectively) of 10mls thrice daily for a year. Result: The repeat serology tests for HIV infection (EIA and Western blot) since 2005 were negative with undetectable viral (HIV-RNA) load. The woman had 3 children (2007, 2010 and 2012) that were breastfed without any of the children infected with HIV and none of the repeat CD4 count was less than 750 cells/ µL. Conclusion: It was concluded by this report that HIV infection in this 27 years old woman completely sero-reverted by a year therapy of Nigella sativa and honey.

Prophetic Medicine-Nigella Sativa (Black cumin seeds) – Potential herb for COVID-19?

“…Similarly, a sustained seroreversion was noted in a 27-year-old HIV infected pregnant woman who was not eligible for antiretroviral therapy, received 10ml of N.sativa and honey mixture (60% of N.sativa seeds and 40% of honey) three times daily for a year. Repeated serology assessments for 10 years have shown undetectable viral load and CD4 count not less than 750 cells/μL [ 18 ].…”

Review on Clinical Trials of Black Seed (Nigella sativa ) and Its Active Constituent, Thymoquinone

“…Similarly, another study conducted by the same author on a sero-positive HIV infected woman revealed the efficacy of NS and honey therapy (10 mL thrice/day for 1 year) for sustained sero-reversion [92]. These effects can be ascribed to the probable virucidal activity of NS [91].…”

“…Onifade et al confirmed that treatment of a sero-positive human immunodeficiency virus (HIV) infected man with NS concoction (10 mL twice/day for six months) resulted in the reduction of the viral load to an undetectable level in 3 months, an elevation of the CD4 count, an alleviation of the symptoms, and a sustained sero-reversion [ 91 ]. Similarly, another study conducted by the same author on a sero-positive HIV infected woman revealed the efficacy of NS and honey therapy (10 mL thrice/day for 1 year) for sustained sero-reversion [ 92 ]. These effects can be ascribed to the probable virucidal activity of NS [ 91 ].…”

“…Highly active anti-retroviral therapy does not cause sero-reversion in HIV-infected patients. Onifade et al proved that NS contributes to sustained sero-reversion in patients with HIV infection [ 91 , 92 ].…”

Nigella sativa L. (Black Cumin): A Promising Natural Remedy for Wide Range of Illnesses

“…The repeat serology assessments for HIV infection became negative with undetectable viral load. The woman also got 3 children (2007, 2010, and 2012) that all were breastfed and none of the children infected with HIV and her repeat CD4 count was not less than 750 cells/ μ L [118]. Nowadays HIV/AIDS is a serious global threat and in this regard, N. sativa can be a promising natural therapy to cure such a chronic infectious disease, after validating its full therapeutic efficacy by further investigations.…”