Serological survey of antibodies to Toxoplasma gondii and Neospora caninium in goat population in Canary Islands (Macaronesia Archipelago, Spain)

Rodríguez-Ponce, Eligia; Conde, M.; Corbera, Juan Alberto; Jaber, José Raduán; Ventura, M.R.; Gutiérrez, Carlos

doi:10.1016/j.smallrumres.2016.11.020

Cited by 8 publications

(2 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nevertheless, studies conducted on livestock in the same island revealed a notable decrease in toxoplasmosis seroprevalence over time. Specifically, the prevalence declined from 68% in 1995 to 9.8% in 2017, showing an overall prevalence of 7.8% for goats, the predominant livestock species in the Canary Islands [49]. The authors attribute this decline to advancements in animal production practices at the farm level, mirroring a global trend in reducing toxoplasmosis prevalence in livestock.…”

Section: Discussionmentioning

confidence: 93%

Toxoplasma gondii Infection in Humans: A Comprehensive Approach Involving the General Population, HIV-Infected Patients and Intermediate-Duration Fever in the Canary Islands, Spain

Carranza-Rodríguez,

Bolaños-Rivero,

Pérez-Arellano

2024

Diagnostics

View full text Add to dashboard Cite

A prior investigation in 1993 identified a high seroprevalence of toxoplasmosis (63%) in the Canary Islands. This study aims to assess the current prevalence of the disease in diverse population groups. The study was based on a population-scale screening involving 273 residents utilizing T. gondii IgG ELISA and a 20 year retrospective study (1998–2018). This included AIDS/HIV outpatients (1357, of which 324 were residents), AIDS/HIV hospitalized patients (741) and patients with fever of intermediate duration (158). The seroprevalence in the resident population was 37%, with significant differences between islands. Among resident outpatients with AIDS/HIV, 14.2% had specific anti-T. gondii IgG, and three had anti-T. gondii IgM; however, IgG avidity testing indicated non-active infection. In patients hospitalized for AIDS/HIV, T. gondii causing encephalitis was detected in 2%. Among patients with fever of intermediate duration, 28.5% were positive for T. gondii IgG, and four also showed IgM positivity, although the infection was non-active. The study reveals a decrease in human toxoplasmosis over the past 30 years. However, the current seroprevalence, which stands at 37%, together with the substantial risk that T. gondii represents for immunocompromised individuals, highlights the need to implement preventive and control strategies to control the threat that this infection can pose to public health in the Canary Islands population.

show abstract

Section: Discussionmentioning

confidence: 93%

Toxoplasma gondii Infection in Humans: A Comprehensive Approach Involving the General Population, HIV-Infected Patients and Intermediate-Duration Fever in the Canary Islands, Spain

Carranza-Rodríguez,

Bolaños-Rivero,

Pérez-Arellano

2024

Diagnostics

View full text Add to dashboard Cite

show abstract

“…The worldwide prevalence of T. gondii among small ruminants varies widely across countries, in both sheep (minimum of 3% in China to a maximum of 94.8% in the USA) and goats (minimum of 7.8% in Spain to a maximum of 90% in Egypt) [26][27][28][29]. We hypothesized that many factors could be associated with this variation, such as geographical and climatic factors, sample size, age of animals, density of infected cats shedding oocysts, type of production or management system, access to contaminated feed and water, techniques used to diagnose infection, as well as the sensitivity-specificity of the testing kits used and their cut-off points.…”

Section: Discussionmentioning

confidence: 99%

Genetic characterization of Toxoplasma gondii in meat-producing animals in Iran

et al. 2022

View full text Add to dashboard Cite

Background The consumption of uncooked or undercooked food from infected intermediate hosts can result in Toxoplasma gondii infection in humans. However, few studies have investigated the genetic diversity of this protozoan parasite in Iran. The aim of the present study was to genetically characterize isolates of T. gondii from intermediate host animals in Mazandaran Province, Iran. Methods Blood and heart tissue samples were collected from 204 ruminants, and brain tissue was collected from 335 birds. The prevalence of T. gondii infection in these samples was determined serologically using the modified agglutination test and by conventional PCR assays. Those PCR samples positive for T. gondii DNA and 13 DNA samples extracted from aborted fetuses in a previous study were genotyped with 12 genetic markers using the multilocus-nested PCR-restriction fragment length polymorphism (Mn-PCR–RFLP) technique. Results Antibodies for parasites were found in 35.7% of the ruminant (39.1% of sheep and 26.4% of goats) samples and in 51.3% of the bird (100% of geese, 52.3% of free-range chickens and 46% of ducks) samples. Molecular detection by PCR of the repetitive 529-bp DNA fragment revealed contamination of 13.2% of ruminant (14.6% of sheep and 9.4% of goats) samples and of 9.6% of bird (11.1% of chickens, 5.7% of ducks and 0% of geese samples). The results from 30 DNA samples revealed five ToxoDB (genome database for the genus Toxoplasma) PCR–RFLP genotypes, including #1 (Type II), #2 (Type III), #10 (Type I), #27 and #48, with genotype #1 the most predominant. Conclusions As evidenced by the results of this study, ruminants and birds are infected with T. gondii in the region, suggesting that they are likely to be involved in the transmission of T. gondii to humans through meat consumption. The identification of different genotypes may suggest a higher genetic diversity of this parasite in Mazandaran, reflecting local environmental contamination. These results have important public health implications for the prevention and control strategies of infection. Graphical Abstract

show abstract

A systematic literature review and meta-analysis of Toxoplasma gondii seroprevalence in goats

et al. 2022

View full text Add to dashboard Cite

Serological survey of antibodies to Toxoplasma gondii and Neospora caninium in goat population in Canary Islands (Macaronesia Archipelago, Spain)

Cited by 8 publications

References 27 publications

Toxoplasma gondii Infection in Humans: A Comprehensive Approach Involving the General Population, HIV-Infected Patients and Intermediate-Duration Fever in the Canary Islands, Spain

Toxoplasma gondii Infection in Humans: A Comprehensive Approach Involving the General Population, HIV-Infected Patients and Intermediate-Duration Fever in the Canary Islands, Spain

Genetic characterization of Toxoplasma gondii in meat-producing animals in Iran

A systematic literature review and meta-analysis of Toxoplasma gondii seroprevalence in goats

Contact Info

Product

Resources

About