2020
DOI: 10.1016/j.htct.2019.08.004 View full text |Buy / Rent full text
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Abstract: Background We evaluated different technological approaches and anti-D clones to propose the most appropriate serologic strategy in detecting the largest numbers of D variants in blood donors. Methods We selected 101 samples from Brazilian blood donors with different expressions of D in our donor routine. The tests were performed in immediate spin (IS) with eleven commercially available anti-D reagents in a tube and microplate. The D confirmatory tests for the presence o… Show more

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“…While RHCE*CeRN and RHD*D‐CE(4–7)‐D underlie cases of weak C and e among people of African descent, and RHCE*JAL and RHCE*ceMO justify weak c and e in this same population, other RHCE alleles encode weak antigens among Caucasians ( RHCE*CeVA , RHCE*CeMA , and RHCE*cE I to IV ) 5–7 . Even though there are descriptions of the distribution of variant RHD among people of multiethnic ancestry, 8–10 data referring to the variant RHCE encoding weak antigens in mixed populations, such as Brazilians, are yet incomplete and may be important information, considering some genotypes can be associated with the risk of alloimmunization.…”
Section: Introductionmentioning
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“…While RHCE*CeRN and RHD*D‐CE(4–7)‐D underlie cases of weak C and e among people of African descent, and RHCE*JAL and RHCE*ceMO justify weak c and e in this same population, other RHCE alleles encode weak antigens among Caucasians ( RHCE*CeVA , RHCE*CeMA , and RHCE*cE I to IV ) 5–7 . Even though there are descriptions of the distribution of variant RHD among people of multiethnic ancestry, 8–10 data referring to the variant RHCE encoding weak antigens in mixed populations, such as Brazilians, are yet incomplete and may be important information, considering some genotypes can be associated with the risk of alloimmunization.…”
Section: Introductionmentioning