Infectious Disease Clinics of North America volume 20, issue 1, P47-61 2006 DOI: 10.1016/j.idc.2006.01.005 View full text
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Julie C. Servoss, Lawrence S. Friedman

Abstract: Serologic assays for HBV are the mainstay diagnostic tools for HBV infection. However, the advent of molecular biology-based techniques has added a new dimension to the diagnosis and treatment of patients with chronic HBV infection. Over the past decade, improvements in molecular technology, permitting detection of as few as 10 copies/mL of HBV DNA in serum have led to redefinitions of chronic HBV infection, as well as thresholds for antiviral treatment. As the sensitivity of these molecular techniques continu…

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