Seroepidemiology of hepatitis B virus infection: analysis of mass screening in Hawaii

Tsai, Naoky; Holck, Peter; Ricalde, Aldrich

doi:10.1007/s12072-008-9103-0

Cited by 15 publications

(12 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…On the other hand, living in a rural area was not found as a risk factor for transmission of hepatitis B. Some studies have reported that there was a significant seropositivity difference between rural and urban regions 20, 26. There are 56 ethnic groups in China and the lifestyle of the minority ethnic population is considerably different from the Han majority ethnic population.…”

Section: Discussionmentioning

confidence: 96%

Seroprevalence and Risk Factors for Hepatitis B Infection in an Adult Population in Northeast China

Zhang¹,

Li²,

Sun³

et al. 2011

Int. J. Med. Sci.

View full text Add to dashboard Cite

Background and aim: The prevalence of the hepatitis B virus (HBV) is higher in adults than in children. We determined the seroepidemiology of HBV infection in an adult population in JiLin, China, to guide effective preventive measures.Methods: A cross-sectional serosurvey was conducted throughout JiLin, China. A total of 3833 people was selected and demographic and behavioral information gathered. Serum samples were tested for HBV markers and liver enzymes.Results: The prevalence of the hepatitis B surface antigen (HBsAg), the antibody to the hepatitis B surface antigen (anti-HBs), the hepatitis B e antigen (HBeAg), the antibody to HBeAg (anti-HBe), and the antibody to the hepatitis B core antigen (anti-HBc) were 4.38%, 35.66%, 1.38%, 6.65%, and 40.88%, respectively. Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels were significantly higher among HBsAg (+) than HBsAg (-) subjects. By multivariate logistic regression analysis, independent predictors for chronic HBV infection were smoking, poor sleep quality; occupation as private small-businessmen, laborers, or peasants; male gender; family history of HBV; personal history of vaccination; and older age. Independent predictors for exposure to HBV were large family size, occupation as a private small-businessman, male gender, family history of HBV, personal history of vaccination, and older age. Independent predictors for immunity by vaccination were occupation as a private small-businessman, high income, personal history of vaccination, and young age. Independent predictors for immunity by exposure were drinking, male gender, personal history of vaccination, and older age.Conclusions: The prevalence rate of HBV infection (4.38%) was lower than the previous rate of general HBV vaccination. However, 44.59% of the population remained susceptible to HBV. The prevalence of HBV infection was high in young adults, private small-businessmen, peasants, those with a family history of HBV, and males. Therefore, immunization of the non-immune population is reasonable to reduce hepatitis B transmission between adults.

show abstract

Section: Discussionmentioning

confidence: 96%

Seroprevalence and Risk Factors for Hepatitis B Infection in an Adult Population in Northeast China

Zhang¹,

Li²,

Sun³

et al. 2011

Int. J. Med. Sci.

View full text Add to dashboard Cite

show abstract

“…However, it is likely that the findings are related to differences in lifestyle or behaviors among males and females, such as smoking, drinking, extensive social range, physical activity, dining out, hygiene, and sexual activity. Luo et al and Tsai et al reported that inhabitants of the plain regions had lower rates of infection than those living in island regions (7, 19). However, differences in HBeAg positivity among regions have remained unknown.…”

Section: Discussionmentioning

confidence: 98%

Serolological Profile Among HBsAg-Positive Infections in Southeast China: A Community-Based Study

Chen¹,

Yu²,

Wu³

et al. 2013

Hepat Mon

View full text Add to dashboard Cite

BackgroundHepatitis B virus (HBV) infection has remained a significant public health problem. Generating a large-scale, community-based profile of HBV infection in China is essential to prevention of the disease.ObjectivesThe current study was designed to investigate HBV-infected individuals at the community level and determine the age distribution, hepatitis B e antigen (HBeAg) positivity and its related risk factors, relationship among serological markers.Patients and MethodsA cross-sectional, community-based survey was carried out without age restriction, in 12 communities of two counties. The study population was selected by random multistage cluster sampling. Serological samples and demographic information were collected from 8439 HB surface antigen (HBsAg)-positive individuals.ResultsThe constituent ratio of individuals with HBsAg-positive infections was lowest among persons aged < 20 years (0.4%) and the highest among persons aged 40-49 years (33.2%). The HBeAg-positive rate among infected individuals was 18.5%, and the constituent ratio decreased with increasing of age. The HBeAg-positive rate in males (21.9%) was significantly higher than in females (14.7%), and was higher among coastland inhabitants (22.9%) than among plains inhabitants (12.9%). Among the 1561 HBeAg-positive individuals, 91.0% were HBV DNA-positive. However, of the 6878 HBeAg-negative individuals, only 45.4% were HBV DNA-positive, and the HBeAg-positive rate was significantly different at different levels of HBV DNA expression. The proportion of detectable HBV DNA levels was significantly higher in individuals with elevated ALT, compared to those with normal ALT, regardless of HBeAg-positivity.ConclusionsThe HBV prevalence remained high in the > 20 age group. The positivity of HBeAg was related to age, region, and sex. Testing HBeAg and serum ALT levels were effective ways to assess HBV infectiousness in community-level hospitals in China.

show abstract

“…A convenience sample of patients screened for hepatitis B at health fairs and clinic settings in Hawaii found that 10.7% of Pacific Islanders were seropositive for Hepatitis B (Tsai, Holck, Wong, and Ricalde, 2008).…”

Section: Hepatitis Bmentioning

confidence: 99%

Micronesian Migrant Health Issues in Hawaii

Yamada

Pobutsky

2009

CALIF J HEALTH PROMOT

View full text Add to dashboard Cite

Increasing numbers of people from the Federated States of Micronesia and the Republic of the Marshall Islands are presenting for clinical and public health services across the U.S., especially in Hawaii. We review the impact of historical and contemporary relationships between the U.S. and these Freely Associated States on the health status and health care access of these migrants. We draw upon both epidemiological evidence and clinical experience to suggest measures to assure health care access and appropriate clinical care for these populations. We also point to potential public health measures, and indicate directions for future research.

show abstract

Seroepidemiology of hepatitis B virus infection: analysis of mass screening in Hawaii

Cited by 15 publications

References 34 publications

Seroprevalence and Risk Factors for Hepatitis B Infection in an Adult Population in Northeast China

Seroprevalence and Risk Factors for Hepatitis B Infection in an Adult Population in Northeast China

Serolological Profile Among HBsAg-Positive Infections in Southeast China: A Community-Based Study

Micronesian Migrant Health Issues in Hawaii

Contact Info

Product

Resources

About