Abstract:Septins play important roles in many cellular processes. Pfanzelter et al. show that septins suppress the release of vaccinia virus from infected cells by trapping virions on the plasma membrane. This antiviral effect is overcome by dynamin and formin-mediated actin polymerization.
scite is a Brooklyn-based startup that helps researchers better discover and evaluate scientific articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by researchers from dozens of countries and is funded in part by the National Science Foundation and the National Institute of Drug Abuse of the National Institutes of Health.