Septic shock due to Clostridium tertium in an immunocompetent patient following colitis without inflammatory bowel disease

Chalhoub, Viviane; Kallab, Rita; Hajj, Albert El; Hachem, K.; Yazbeck, Patricia

doi:10.1016/j.accpm.2015.10.007

Cited by 9 publications

(11 citation statements)

References 5 publications

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“…This patient’s abscess was treated with drainage and metronidazole [12]. Another reported case involved a non-neutropenic patient that initially presented with colitis that was later found to have C. tertium bacteremia successfully treated with ampicillin, vancomycin, and imipenem [13].…”

Section: Discussionmentioning

confidence: 99%

Clostridium tertium bacteremia and hepatic abscess in a non-neutropenic patient

Milano

Biehle

Patel

et al. 2019

IDCases

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A 43-year-old previously healthy man presented with altered mental status, diaphoresis, and fevers following a ruptured appendicitis and appendectomy. The patient had growth of Clostridium tertium and Escherichia coli in blood cultures and imaging of the abdomen revealed a large hepatic abscess. Clostridium tertium is an uncommon cause of bacteremia in non-neutropenic patients. There is currently no universally accepted treatment for Clostridium tertium bacteremia. We report successful treatment with ertapenem.

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Section: Discussionmentioning

confidence: 99%

Clostridium tertium bacteremia and hepatic abscess in a non-neutropenic patient

Milano

Biehle

Patel

et al. 2019

IDCases

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“…C. tertium has been implicated in abdominal infections, but this is the first reported case of PLA cause by this pathogen. 14 - 16 Although more common in neutropenic patients, there are reports of fatal infections in immunocompetent patients. 17 PLA should be identified promptly and treated aggressively with a prolonged course of antimicrobials, and serial imaging studies are necessary to confirm adequate response and resolution.…”

Section: Discussionmentioning

confidence: 99%

Clostridium tertium: An Unusual Cause of Pyogenic Liver Abscess

Barakat

Hernandez

Benoit

et al. 2018

ACG Case Reports Journal

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Pyogenic liver abscess (PLA) is the result of portal vein pyemia, which usually originates from the hepatobiliary system or the gastrointestinal tract. Gram-negative organisms are the most common causative pathogens in PLA. Clostridium tertium is an anaerobic gram-positive, low-virulence organism that most commonly affects neutropenic patients with hematological malignancy and has not been reported to cause PLA. We report an unusual presentation of a C. tertium infection as a PLA in a previously healthy, immunocompetent patient with no identifiable source of portal pyemia.

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“…While the majority of C tertium cases are associated with patients with neutropenia, there are cases demonstrating that C tertium is an important cause in a non-neutropenic patient. 5 , 8 , 10 , 13 …”

Section: Discussionmentioning

confidence: 99%

Clostridium tertiumPeritonitis and Concurrent Bacteremia in a Patient With a History of Alcoholic Cirrhosis

Sutton

Jumper

Shah

et al. 2017

Journal of Investigative Medicine High Impact Case Reports

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Spontaneous bacterial peritonitis (SBP) is a recognized cause of morbidity and mortality in cirrhotic patients. Enterobacteriaceae have been isolated from the majority of peritonitis cases and the gram negative aerobe Escherichia coli is the most commonly isolated organism. Anaerobic organisms are rarely isolated because of the high oxygen tension in ascetic fluid. We report a patient with a history of alcoholic cirrhosis who developed SBP and concurrent bacteremia with the anaerobe Clostridium tertium. The patient was successfully treated with intravenous antibiotics and was discharged home on oral ciprofloxacin. This case report is unique in that it is the fourth documented Clostridium tertium SBP case, utilized MALDI-TOF mass spectrometry for organism identification, and susceptibility testing for select antibiotics was performed.

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Septic shock due to Clostridium tertium in an immunocompetent patient following colitis without inflammatory bowel disease

Cited by 9 publications

References 5 publications

Clostridium tertium bacteremia and hepatic abscess in a non-neutropenic patient

Clostridium tertium bacteremia and hepatic abscess in a non-neutropenic patient

Clostridium tertium: An Unusual Cause of Pyogenic Liver Abscess

Clostridium tertiumPeritonitis and Concurrent Bacteremia in a Patient With a History of Alcoholic Cirrhosis

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