Journal of Chromatography A 2012 DOI: 10.1016/j.chroma.2011.12.102 View full text
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Elisabeth Hopmann, Mirjana Minceva

Abstract: Sequential centrifugal partition chromatography (sCPC) is a novel continuous cyclic liquid-liquid chromatographic separation technology. Each cycle of the process comprises two steps, which differ by the liquid phase used as mobile phase (upper or lower phase) and its flow direction. The feed is introduced continuously in the unit and two product streams are collected alternately, in each step of the cycle. In this work, the sCPC was modeled using the stage (cell) model. The model was used to simulate a separa…

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