Sensitive determination of 17β-estradiol in river water using a graphene based electrochemical sensor

Moraes, Fernando C.; Rossi, Bruno Roberto; Donatoni, Maria Carolina; Oliveira, Kléber T. de; Pereira, Ernesto C.

doi:10.1016/j.aca.2015.04.043

Cited by 113 publications

(75 citation statements)

References 37 publications

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“…Although different electrochemical methods have been developed for the individual determination of DES [5][6][7] and E2 [8][9][10][11], the studies regarding the simultaneous determination of DES and E2 are very rare [12]. More importantly, the sensitivity of the reported electrochemical methods is relatively low.…”

Section: Introductionmentioning

confidence: 97%

Simultaneous determination of environmental estrogens: Diethylstilbestrol and estradiol using Cu-BTC frameworks-sensitized electrode

Wang

et al. 2016

Talanta

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Section: Introductionmentioning

confidence: 97%

Simultaneous determination of environmental estrogens: Diethylstilbestrol and estradiol using Cu-BTC frameworks-sensitized electrode

Wang

et al. 2016

Talanta

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“…In the European Union pharmaceuticals authorization procedures include Comission directives, which contain a requirement to develop a strategic approach to the pollution of water by pharmaceutical substances. E2 and EE2 were newly added to the EU watch list of emerging pollutants Ke et al 2014, Skotnicka-Pitak et al 2008) and immunoassays (Franke et al 2011, Moraes et al 2015, Tan &Wei 2015, but chromatographic based methods with UV-VIS, fluorescence or electrochemical detection are also available (Popescu et al 2008, Xu et al 2013, Zou et al 2014. Estrogenic activity can be determined by biological monitoring approaches.…”

Section: Introductionmentioning

confidence: 99%

β-Estradiol and ethinyl-estradiol contamination in the rivers of the Carpathian Basin

Avar

Zrínyi²,

Maász

et al. 2016

Environ Sci Pollut Res

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17β-estradiol (E2) and 17α-ethinyl estradiol (EE2), which are environmental estrogens have been determined with LC-MS in freshwater. Their sensitive analysis needs derivatisation and therefore is very hard to achieve in multiresidue screening. We analysed samples from all the large and some small rivers (River Danube, Drava, Mur, Sava, Tisza and Zala) of the Carpathian Basin and from Lake Balaton. Freshwater was extracted on solid phase and derivatised using dansyl-chloride. Separation was performed on a Kinetex XB-C18 column. Detection was achieved with a benchtop orbitrap mass spectrometer using targeted MS analysis for quantification. Limits of quantification were 0.05 ng/L (MS1) and 0.1 ng/L (MS/MS) for E2, and 0.001 ng/L (MS1) and 0.2 ng/L (MS/MS) for EE2. River samples contained n.d.-5.2 ng/L E2 and n.d.-0.68 ng/L EE2. Average levels of E2 and EE2 were 0.61 and 0.084 ng/L respectively in rivers, water courses and Lake Balaton together, but not counting city canal water. EE2 was less abundant, but it was still present in almost all of the samples. In beach water samples from Lake Balaton we measured 0.076-0.233 E2 and n.d.-0.133 EE2. A relative high amount of EE2 was found in river Zala (0.68 ng/L) and in Hévíz-Páhoki canal (0.52 ng/L), which are both in the catchment area of Lake Balaton (Hungary). HighlightsMethod is proposed for simultaneous determination of 17β-estradiol and 17α-ethinyl estradiol. Derivatization is necessary to reach low LOQ. Low ng/L presence of estrogens in selected European Rivers has been detected.

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“…[46][47][48][49] Therefore recent advancements have been reported where electrochemistry is combined to nanotechnology and molecular biology. [46][47][48][49] Therefore recent advancements have been reported where electrochemistry is combined to nanotechnology and molecular biology.…”

Section: Recent Advancements In Detection Methodsmentioning

confidence: 99%

Recent advancements in analytical methods for the determination of steroidal estrogen residues in environmental and food matrices

Gunatilake¹,

Munasinghe²,

Ranaweera³

et al. 2016

Anal. Methods

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Residue steroidal estrogens in environmental and food samples have become a cause for concern as they can affect organisms at low ppt concentrations. Analytical method development plays a key role in trace estrogen analysis due to the combination of low concentrations and complicated sample matrices. Reliable quantification of these trace level steroidal estrogens has become a major concern during the past decade. This mini review focuses on advancements in analytical methods developed for estrogen detection and quantification in environmental and food samples from 2014 -2016. A comprehensive overview of the novelties and the advantages of the recently developed sample pre-concentration, clean-up, and detection methods are discussed. During the past three years, a wide variety of sample extraction methods including, the utilization of innovative imprinted magnetic sorbents, QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) method and various microextraction methods such as Dispersive liquid-liquid micro extraction (DLLME), Thin film micro extraction (TFME), Solid phase microextraction (SPME), and Vortex assisted hollow fiber liquid-phase micro extraction (VA-HF-LPME) have been

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Sensitive determination of 17β-estradiol in river water using a graphene based electrochemical sensor

Cited by 113 publications

References 37 publications

Simultaneous determination of environmental estrogens: Diethylstilbestrol and estradiol using Cu-BTC frameworks-sensitized electrode

Simultaneous determination of environmental estrogens: Diethylstilbestrol and estradiol using Cu-BTC frameworks-sensitized electrode

β-Estradiol and ethinyl-estradiol contamination in the rivers of the Carpathian Basin

Recent advancements in analytical methods for the determination of steroidal estrogen residues in environmental and food matrices

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