Semi-Automatic 3D Reconstruction of Atheroma Plaques from Intravascular Ultrasound Images Using an ad-hoc Algorithm

Abstract

The occurrence of atheroma plaques in the arteries can eventually obstruct them, leading to diseases such as atherosclerosis, which can cause, among others, a myocardial infarction or a stroke. As a consequence, it is necessary to shorten the time spent in locating and reconstructing the atheroma plaque that can be developed in an artery. This localization is usually conducted manually from the contours located on the cross-sectional radiographs of the artery and then reconstructed by creating the volumes using different techniques. This paper presents a 3-D reconstruction of the atheroma plaque by applying an image processing algorithm ad-hoc developed in order to obtain the boundaries of the atheroma, from a set of intravascular ultrasound images. The advantage of the approach developed in this paper is that it can be implemented in common medical procedures, as an important complementary decision-support tool. By reconstructing the atheroma instead of the artery, this work provides a different approach to improve its location and treatment. Results presented herein can be implemented in machine-learning-based algorithms, able to predict the growth and extent of incipient atheroma plaques, which ultimately contribute to an early detection of this pathology.

Temporal Evaluation of the Surface Area of Treated Skin Ulcers Caused by Cutaneous Leishmaniasis and Relation with Optical Parameters in an Animal Model: A Proof of Concept

“…The processing of the acquired images started by selecting 50 frames extracted from each video (Figure 2a). This number of frames was established as optimal to have better computational performance with the Agisoft PhotoScan software, based on the 3D reconstruction of multiple views from still images [24] in which the frames were loaded to obtain 3D reconstructions [25][26][27][28]. Reconstruction was carried out using a series of intuitive commands designed for this purpose.…”