2008
DOI: 10.1007/s11102-008-0161-z
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Abstract: Germ cell tumors (GCT) are a heterogeneous group of lesions whose origin is not well established. Several cases of primary intrasellar germinomas have been reported, however non-germinomatous GCT have rarely been described. We report the case of a young adult male patient with a mixed GCT that presented with a sellar tumor with suprasellar extension. The patient seeked medical attention because of seizures and magnetic resonance imaging evidenced a tumor of the sellar region. Hyperprolactinemia was also presen… Show more

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Cited by 15 publications
(11 citation statements)
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“…Ряд проведенных исследований [11][12][13][14][15] продемонстрировал нарушения секреции гормонов гипофиза при компрессии СГ различными объемными образованиями ХСО, такими как АГ, менингиомы, КФ, герминомы, глиомы, воспалительные процессы (туберкулез, саркоидоз), метастазы, аневризмы сонной артерии. Пациенты с компрессией СГ и портальных сосудов имеют умеренную гиперпролактинемию и снижение секреции гипофизарных гормонов.…”
Section: Discussionunclassified
“…Ряд проведенных исследований [11][12][13][14][15] продемонстрировал нарушения секреции гормонов гипофиза при компрессии СГ различными объемными образованиями ХСО, такими как АГ, менингиомы, КФ, герминомы, глиомы, воспалительные процессы (туберкулез, саркоидоз), метастазы, аневризмы сонной артерии. Пациенты с компрессией СГ и портальных сосудов имеют умеренную гиперпролактинемию и снижение секреции гипофизарных гормонов.…”
Section: Discussionunclassified
“…In addition to 3 sellar chordomas found to be with elevated serum prolactin level from 1966 to 2000 [1] , another 2 cases had been reported in recent 10 years [2,3] . Besides sellar chordomas, other sellar tumors such as schwannoma, paraganglioma or mixed germ cell tumor could also lead to hyperprolactinemia [4][5][6] and they were regarded as pseudo-macroprolactinoma as well. Despite the mechanism underlying the higher level of serum prolactin produced by these pseudomacroprolactinomas is not fully understood, pituitary stalk compression syndrome was proposed to explain this phenomenon.…”
Section: Discussionmentioning
confidence: 99%
“…Despite these two types of tumors are similar on MRI, the prolactin level of a sellar chordoma used to be half of that of a typical pituitary prolactinomas (3,000 mIU/L), which could be used as a key point in differential diagnosis. Other sellar tumors leading to elevated prolactin also include meningioma, craniopharygioma, schwannoma, paraganglioma, neuroblastoma or mixed germ cell tumor [4][5][6][7][8][9] . Just as in our case, the higher levels of prolactin induced by these tumors were thought to be caused by pituitary stalk compression, so that their prolactin level is not as high as that in the typical pituitary prolactinomas.…”
Section: Discussionmentioning
confidence: 99%
“…Suprasellar germ cell tumor (GCT) has been reported rarely in human beings 1,8,14,16,21 and dogs. 13,20 In general, masses arising from the suprasellar region cause clinical signs consistent with pituitary dysfunction 14 ; blindness, exophthalmos, obtundation, mydriasis, ptosis, and polyuria have also been reported.…”
mentioning
confidence: 99%
“…Germ cell tumors in this region can present similarly to pituitary adenomas, or with blindness, due to proximity or local extension into the pituitary gland or optic chiasm, respectively. 21 …”
mentioning
confidence: 99%