Self-healing juvenile cutaneous mucinosis

Caputo, R.

doi:10.1001/archderm.131.4.459

Cited by 8 publications

(13 citation statements)

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“…Finally, hard periorbital edema developed, similar to that described by Caputo, Grimalt, and Gelmetti. 3 This was perhaps the most striking clinical finding in our patient.…”

Section: Discussionsupporting

confidence: 58%

“…Small, nontender, flesh-colored papules are commonly seen on the head, neck, trunk, and periarticular areas and may have a corrugated appearance. [1][2][3][4][5][6]8 In our patient, these lesions were most pronounced over the knuckles of the hands, on the forehead, and extensor surfaces of the knees. Deep nodules typically develop on the face, scalp, and periarticular regions.…”

Section: Discussionmentioning

confidence: 63%

“…Eight subsequent cases have been described in the literature in the last 30 years, only 2 of which have been from the United States. [2][3][4][5][6][7][8][9] Of the 9 reported patients, 6 have been male. Early reports described patients between 5 and 15 years of age.…”

Section: Discussionmentioning

confidence: 99%

“…Early reports described patients between 5 and 15 years of age. [2][3][4][5][6][7] However, in the last year 2 younger patients have been reported with disease onset at 14 and 23 months. 8,9 Bonerandi et al 7 proposed that SHJCM is a distinct mucinosis characterized by the following criteria: young age at onset; peculiar distribution of cutaneous lesions; presence of deep nodules on face and periarticular regions; absence of systemic findings (dysglobulinemia, bone marrow plasmacytosis, or thyroid dysfunction); and acute onset followed by spontaneous resolution.…”

Section: Discussionmentioning

confidence: 99%

“…A mild perivascular or diffuse mononuclear cell infiltrate is seen. 2,3,6 In most cases, alcian blue staining at pH of 2.5 has identified the mucinous material to be predominantly hyaluronic acid. Alcian blue at pH 0.5 and periodic acidϪSchiff staining are usually negative.…”

Section: Discussionmentioning

confidence: 99%

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Self-healing juvenile cutaneous mucinosis

Cowen

Scott

Mercurio

2004

Journal of the American Academy of Dermatology

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“…Finally, hard periorbital edema developed, similar to that described by Caputo, Grimalt, and Gelmetti. 3 This was perhaps the most striking clinical finding in our patient.…”

Section: Discussionsupporting

confidence: 58%

Section: Discussionmentioning

confidence: 63%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Self-healing juvenile cutaneous mucinosis

Cowen

Scott

Mercurio

2004

Journal of the American Academy of Dermatology

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Self‐Healing Juvenile Cutaneous Mucinosis

Carder

Fitzpatrick

Weston

et al. 2003

Pediatric Dermatology

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A healthy 14-month-old black girl presented with a 3-week complaint of "knots" on the face and hands. The lesions were acute in onset and asymptomatic. Multiple, firm, nontender, skin-colored to erythematous nodules were noted on the scalp, forehead, axillae, lower legs, abdomen, and hands. A skin biopsy specimen revealed a well-circumscribed accumulation of mucin in the reticular dermis. Colloidal iron stain was positive. Radiographs showed soft tissue prominence only. Serum protein electrophoresis, thyroid function tests, complete blood count, sedimentation rate, and antinuclear antibody were normal, except for lymphocytosis. Findings were consistent with self-healing juvenile cutaneous mucinosis (SHJCM). SHJCM is a condition of unknown etiology characterized by rapid onset of asymptomatic, indurated papules or nodules. Affected children may have arthralgias, but are otherwise well. Spontaneous resolution is the rule. Most skin lesions in our patient had resolved within 6 months of onset. This patient is unique because of the young age of onset.

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Cutaneous Mucinoses

Rongioletti

Rebora

2001

The American Journal of Dermatopathology

164

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The clinical aspects and the histologic features of cutaneous mucinoses have been reviewed and their classification updated. Cutaneous mucinoses are divided into distinctive (primary) cutaneous mucinoses in which the mucin deposit is the main histologic feature resulting in clinically distinctive lesions, and disorders associated with histologic mucin deposition as an additional finding (secondary mucinoses). The former are further divided into degenerative-inflammatory mucinoses, which may be either dermal or follicular, and into neoplastic-hamartomatous mucinoses. Histopathologic diagnosis is particularly difficult for dermal mucinoses and requires clinicopathologic correlation. Three histologic clues, namely the pattern of mucin distribution (diffuse or focal), the level of mucin deposit in the dermis and some additional findings may help diagnosis. Follicular mucinoses have the easiest pattern to recognize histologically, but the distinction between Pinkus' follicular mucinosis and follicular mucinosis with mycosis fungoides is very difficult.Lastly, neoplastic-hamartomatous cutaneous mucinoses include mucinous nevus, a benign hamartoma, and myxoma, which is a benign tumor to be differentiated from reactive cutaneous focal mucinosis.

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Self-healing juvenile cutaneous mucinosis

Cited by 8 publications

References 0 publications

Self-healing juvenile cutaneous mucinosis

Self-healing juvenile cutaneous mucinosis

Self‐Healing Juvenile Cutaneous Mucinosis

Cutaneous Mucinoses

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