“…The phenomenon of ACS is a well established theory in colonic adenocarcinoma. This is proven by the genetic analysis and in relation with familial colonic cancer syndromes such as Gardner, Cowden, Turcot syndromes etc., [ 4 , 5 ]. For instance, adenomatous polyposis coli (APC) gene mutation confirmed this ACS in colonic cancer related to familial adenomatous polyposis [ 27 ].…”