2002
DOI: 10.1002/lsm.10080
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Selective photothermolysis of the sebaceous glands for acne treatment

Abstract: ICG and diode laser treatment is a new approach for the treatment of acne based on experimentally observed selective photothermolysis of the sebaceous glands.

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Cited by 104 publications
(92 citation statements)
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“…Long-term follow-up biopsies of similarly treated back and face skin showed no difference from baseline in adnexal structures, including sebaceous glands and follicles. Significantly, research with shorter pulse (810 nm) diode lasers used in combination with indocyanine green (ICG) dye has indicated similar transient necrosis of sebaceous glands followed by long-term improvement of acne [81]. The underlying mechanism of epidermal sparing and dermal injury is consistent with the nonablative paradigm and different from aminolevulinic acid (ALA)-photodynamic therapy (PDT) and other laser/light based acne treatments that achieve their effect by depopulating p. acnes.…”
Section: Diode Laser (1450 Nm)mentioning
confidence: 77%
“…Long-term follow-up biopsies of similarly treated back and face skin showed no difference from baseline in adnexal structures, including sebaceous glands and follicles. Significantly, research with shorter pulse (810 nm) diode lasers used in combination with indocyanine green (ICG) dye has indicated similar transient necrosis of sebaceous glands followed by long-term improvement of acne [81]. The underlying mechanism of epidermal sparing and dermal injury is consistent with the nonablative paradigm and different from aminolevulinic acid (ALA)-photodynamic therapy (PDT) and other laser/light based acne treatments that achieve their effect by depopulating p. acnes.…”
Section: Diode Laser (1450 Nm)mentioning
confidence: 77%
“…Light sources that are used to treat acne vulgaris act by destroying either (1) the sebaceous glands, 94 (2) the entire pilosebaceous unit, or (3) Propionibacterium …”
Section: Acne Vulgarismentioning
confidence: 99%
“…Using these parameters, the group then treated 10 patients with back acne and their preliminary clinical results noted a decrease in acne in the treatment area at 3, 6, and 10 months follow-up. The authors concluded that the success of the combination of ICG and diode laser treatment relies on the ability to induce selective photothermolysis of the sebaceous glands though long-term histologic evaluation of the treatment areas was not performed [52].…”
Section: Photodynamic Therapy (Pdt)mentioning
confidence: 99%