Selective Laser Trabeculoplasty as Primary Treatment for Open-angle Glaucoma

Abstract

To examine the safety and efficacy of selective laser trabeculoplasty as primary treatment for patients with open-angle glaucoma. Methods: Forty-five eyes of 31 patients with openangle glaucoma or ocular hypertension (intraocular pressure [IOP] Ն23 mm Hg on 2 consecutive measurements) underwent selective laser trabeculoplasty as primary treatment. All patients underwent complete ophthalmic evaluation before and at intervals after treatment. This evaluation included visual acuity, slitlamp examination, ophthalmoscopy, gonioscopy, and visual field analysis. The IOP was measured 1 hour, 1 day, 1 week, and 1, 3, 6, 12, 15, and 18 months postoperatively. During the follow-up period, patients were treated with topical antiglaucoma medications as required. Results: Mean ± SD decreased by 7.7±3.5 mm Hg (30%), from 25.5±2.5 mm Hg to 17.9±2.8 mm Hg (PϽ.001). Only 2 eyes (4%) did not respond to selective laser trabeculoplasty, and 3 eyes (7%) required topical medications to control their IOP at the end of the follow-up period. Forty eyes (89%) had a decrease of 5 mm Hg or more. Visual acuity, visual fields, and gonioscopic findings remained unchanged. Complications included conjunctival redness and injection within 1 day postoperatively in 30 eyes (67%). One hour after selective laser trabeculoplasty, an increase in IOP of more than 5 mm Hg was detected in 5 eyes (11%), while an increase in IOP between 2 and 5 mm Hg was measured in 3 eyes (7%). Conclusion: Selective laser trabeculoplasty is effective and safe as a primary treatment for patients with ocular hypertension and open-angle glaucoma.

Intraocular pressure control and fluctuation: the effect of treatment with selective laser trabeculoplasty

“…In our study, both treatment modalities had a significant impact on IOP fluctuation, with SLT successfully lowering IOP fluctuation in 50% of patients and latanoprost in 83% of patients. The response rate and IOP reduction in this present study were comparable with those reported in published literature in which the success rate varies from 64% to 89% 14 – 16…”

Intraocular pressure control and fluctuation: the effect of treatment with selective laser trabeculoplasty

“…In our study, both treatment modalities had a significant impact on IOP fluctuation, with SLT successfully lowering IOP fluctuation in 50% of patients and latanoprost in 83% of patients. The response rate and IOP reduction in this present study were comparable with those reported in published literature in which the success rate varies from 64% to 89% 14 – 16…”

Influence of Selective Laser Trabeculoplasty on 24-Hour Diurnal Intraocular Pressure Fluctuation in Primary Open-Angle Glaucoma: A Pilot Study

“…As in other studies, [13][14]17 the current study found early post-treatment IOP elevation. IOP elevation of greater than 5 mm Hg was found in 62% of eyes within 2 hours after selective laser trabeculoplasty.…”

Five‐year follow up of selective laser trabeculoplasty in Chinese eyes

“…In the medical group, eight eyes with failed maximal medical treatment required filtration surgery. Our results in terms of IOP reductions, number of medications reduction and the failure rate compare favourably with other SLT studies 12−15,17,18 .…”

Intraocular pressure control and fluctuation: the effect of treatment with selective laser trabeculoplasty

“…In our study, both treatment modalities had a significant impact on IOP fluctuation, with SLT successfully lowering IOP fluctuation in 50% of patients and latanoprost in 83% of patients. The response rate and IOP reduction in this present study were comparable with those reported in published literature in which the success rate varies from 64% to 89% 14 – 16…”

Influence of Selective Laser Trabeculoplasty on 24-Hour Diurnal Intraocular Pressure Fluctuation in Primary Open-Angle Glaucoma: A Pilot Study

“…As in other studies, [13][14]17 the current study found early post-treatment IOP elevation. IOP elevation of greater than 5 mm Hg was found in 62% of eyes within 2 hours after selective laser trabeculoplasty.…”

Five‐year follow up of selective laser trabeculoplasty in Chinese eyes

“…In the medical group, eight eyes with failed maximal medical treatment required filtration surgery. Our results in terms of IOP reductions, number of medications reduction and the failure rate compare favourably with other SLT studies 12−15,17,18 .…”

Intraocular pressure control and fluctuation: the effect of treatment with selective laser trabeculoplasty

“…In our study, both treatment modalities had a significant impact on IOP fluctuation, with SLT successfully lowering IOP fluctuation in 50% of patients and latanoprost in 83% of patients. The response rate and IOP reduction in this present study were comparable with those reported in published literature in which the success rate varies from 64% to 89% 14 – 16…”

Influence of Selective Laser Trabeculoplasty on 24-Hour Diurnal Intraocular Pressure Fluctuation in Primary Open-Angle Glaucoma: A Pilot Study

“…As in other studies, [13][14]17 the current study found early post-treatment IOP elevation. IOP elevation of greater than 5 mm Hg was found in 62% of eyes within 2 hours after selective laser trabeculoplasty.…”

Five‐year follow up of selective laser trabeculoplasty in Chinese eyes

“…In the medical group, eight eyes with failed maximal medical treatment required filtration surgery. Our results in terms of IOP reductions, number of medications reduction and the failure rate compare favourably with other SLT studies 12−15,17,18 .…”