Selective Iodine‐Catalyzed Intermolecular Oxidative Amination of C(sp³)H Bonds with ortho‐Carbonyl‐Substituted Anilines to Give Quinazolines

A Rapid and Efficient Access to Polysubstituted Imidazoles viaIodine-Catalyzed Tandem Oxidative Cyclization

“…This imine B could be oxidized into imine cation C in the presence of iodine and TBHP. [16] Then intermediate D was formed via an intramolecular cyclization. After deprotonation the target product was obtained.…”

One-pot three-component synthesis of quinazolines via a copper-catalysed oxidative amination reaction

“…(Scheme 1b). 12 Li proposed a KIcatalysed protocol via amination of benzylic C-H bonds of methylarenes to form quinazoline derivatives (Scheme 1c). 13 In these transformations, peroxides which were excessive and easily exploded at high temperature were used as oxidant.…”

Catalyst‐Controlled Highly Selective Coupling and Oxygenation of Olefins: A Direct Approach to Alcohols, Ketones, and Diketones

“…[17a] In a transition-metal-and iodine-free system, the benzyl peroxy radical 10 couples with the hydroperoxide radical (HOO·) to form a monoalkyl tetroxide 11, which decomposes to afford the desired product 3 a, along with the formation of molecular oxygen and water through Russell fragmentation. [22,23] The by-products benzene, [10a] bibenzyl, and stilbene [24] were detected by GCMS, which indicated that intermediates 8 and 9 are involved in this transformation. [21] Furthermore, intermediate 13, which is generated from 3 a, could be continuously oxidized by Cu-and/or Fesalts and molecular oxygen to form benzyl radical 14, which can undergo the same oxidative processes again (as benzyl radical 9) to form the second carbonyl group of diketone product 4 a.…”