Abstract:Previously, we reported that estrogen receptors (ERα, ERβ) exert differing effects on mesenteric arterial reactivity to vasopressin (VP) and that estrogen enhances constrictor prostanoids by upregulating thromboxane synthase and cyclooxygenase‐2 message in rat aorta. We measured mean arterial blood pressure (BP), thromboxane (TXA2) and prostacyclin (PGI2) release by mesenteric arterioles (200 μm) in normo‐ and aortic coarctation‐induced hypertensive (NT and HT) Sprague‐Dawley female rats that were intact (INT)… Show more
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