Selected physical medicine interventions in the treatment of diabetic foot syndrome

Gebala-Prajsnar, Kamila; Stanek, Agata; Pasek, Jarosław; Prajsnar, Grzegorz; Berszakiewicz, Andrzej; Sieroń, Aleksander; Cholewka, Armand

doi:10.5603/aa.2015.0024

Cited by 11 publications

(11 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among the benefits of this form of therapy are increased oxygenation of hypoxic and ischaemic tissues, improved blood circulation, reduced oedema, and accelerated healing. HBO also has a bactericidal and bacteriostatic effect [ 7 – 9 ]. During the procedure, the patient is placed in a hyperbaric chamber and provided 100% oxygen for breathing [ 10 ], which increases the partial pressure of oxygen in the lungs, increases plasma oxygen concentration compared with normal conditions, and significantly increases the oxygen diffusion radius from capillaries to the surrounding tissues [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Oxidative Stress in Patients with Difficult-to-Heal Skin Wounds Treated with Hyperbaric Oxygen

Paprocki

Pawłowska

Sutkowy

et al. 2020

Oxidative Medicine and Cellular Longevity

View full text Add to dashboard Cite

Objective. To determine the concentration of thiobarbituric acid reactive substances (TBARS) in erythrocytes and blood plasma, and the activities of selected antioxidant enzymes: catalase (CAT), superoxide dismutase (SOD), and glutathione peroxidase (GPx) in erythrocytes in patients receiving hyperbaric oxygen (HBO) treatment due to difficult-to-heal “skin wounds”. Material and Methods. Indices of oxidative stress were assessed in venous blood taken from 23 patients three times: immediately before HBO procedure, approx. 5 minutes after leaving the hyperbaric chamber, and after 25 HBO procedures. Moreover, selected blood counts were measured in the collected material two times: prior to treatment and after 25 HBO procedures. Results. A statistically significant positive correlation between the CAT activity and the TBARS concentration in the erythrocytes of patients was found before treatment in the hyperbaric chamber (r=0.394; P≤0.05). No statistically significant changes in the TBARS concentration in erythrocytes and blood plasma were observed both after the first HBO procedure and after 25 procedures. No statistically significant changes in the activities of CAT, SOD, and GPx were noted. Platelet count decreased by 18.7% (P≤0.05) after 25 HBO procedures. Granulocyte count decreased by approx. 21% (P≤0.05), and granulocyte percentage by 11.8% (P≤0.01). In turn, the percentage of lymphocytes and monocytes increased after the treatment by 16.6% (P<0.05) and 16.4% (P<0.05), respectively. Conclusions. Exposure to HBO due to difficult-to-heal skin wounds does not significantly affect the levels of oxidative stress in the peripheral blood of patients and, from the point of view of oxidation–reduction processes, appears to be a safe therapeutic method for the treatment of chronic wounds.

show abstract

Section: Introductionmentioning

confidence: 99%

Evaluation of Oxidative Stress in Patients with Difficult-to-Heal Skin Wounds Treated with Hyperbaric Oxygen

Paprocki

Pawłowska

Sutkowy

et al. 2020

Oxidative Medicine and Cellular Longevity

View full text Add to dashboard Cite

show abstract

“…The diabetic foot syndrome (DFS) is characterized by the presence of infection and/or ulcer, and/or deep tissue destruction as a result of underlying neuropathy and different severity ischemia from peripheral vascular disease. Diabetic patients have up to a 25% lifetime risk of developing diabetic foot syndrome [7].…”

Section: Introductionmentioning

confidence: 99%

“…It is estimated that 5% to 15% of patients with foot ulcers will require amputation, with major lower limb amputations accounting for 50% of these amputations. Over 50% of the amputees will undergo another amputation within five years, (of whom 50% will not survive the next five years) [7], prolonged hospital stays and recurrent ulcers, producing high treatment costs and causing major difficulties for public health systems. These factors may also make patients less able to work, provoke early retirement and lead to difficulty in performing the activities of daily life, generating feelings of helplessness, frustration, vulnerability and a poor body image [9].…”

Section: Introductionmentioning

confidence: 99%

Patient-Reported Outcome Measures for Patients with Diabetes Mellitus Associated with Foot and Ankle Pathologies: A Systematic Review

Ortega-Ávila

Cervera‐Garvi

Ramos‐Petersen

et al. 2019

JCM

View full text Add to dashboard Cite

Background: Diabetes mellitus (DM) is a chronic and complex disease, which is a major cause of morbidity and mortality and affects all age groups. It commonly produces secondary effects on the foot, often making daily activities impossible. Patient-reported outcome measures (PROMs) provide a standardised method of obtaining patients’ outlooks on their functional status and wellbeing. Although many instruments have been proposed for obtaining data on persons with DM whose feet are affected by the disease, in many cases the psychometric properties of the instrument have yet to be established. The principal objective of our review was to identify PROMs specific for patients with DM affecting the foot and ankle and to evaluate the psychometric properties and methodological quality of these instruments. Methods: In this systematic review, we investigate studies (published in English or Spanish) based on the use of one or more PROMs specific to foot and ankle pathologies for patients with DM (type I or II). To do so, the databases PubMed, Scopus, CINAHL, PEDro and Google Scholar were searched for studies that analysed psychometric or clinimetric properties in this respect. These were assessed according to Terwee or COSMIN criteria. Results: Of the 1016 studies identified in the initial search, only 11 were finally included in the qualitative review. Analysis according to Terwee and COSMIN criteria showed that the Foot Health Status Questionnaire (FHSQ) presented the greatest number of positive values. Conclusions: The FHSQ is the highest-quality PROM currently available for the foot and ankle, for patients with DM.

show abstract

“…Consequently, optimizing the local wound condition to reduce these various issues is an important factor to address during pressure ulcer wound care treatment [ 2 ]. Negative pressure wound treatment (NPWT) is a widely used approach for pressure ulcers, helping to promote healing by minimizing intercellular edema and promoting micro-vascularization and granulation tissue formation [ 3 ], elimination of excess exudate from wound surface, improvement of blood supply to wound bed, maintenance of adequate wound humidity and reduction of the microorganism burden on the wound surface [ 4 ]. However, removal of conventional NPWT can cause pain or focal bleeding, delaying wound healing and possibly causing infection [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

A Prospective Randomized Study: The Usefulness and Efficacy of Negative Pressure Wound Therapy with Lipidocolloid Polyester Mesh Compared to Traditional Negative Pressure Wound Therapy for Treatment of Pressure Ulcers

et al. 2020

View full text Add to dashboard Cite

To improve healing of pressure ulcer wounds, it is important to optimize the conditions of the area surrounding the wound. Negative pressure wound therapy (NPWT) promotes wound healing, however, the removal of NPWT can cause pain or focal bleeding, delaying wound healing or causing infection. In this study, we reviewed the efficacy of the lipidocolloid non-adherent dressing (Urgotul®) as a wound contact layer. A total of 38 patients from the same facility who applied NPWT from April 2016 to October 2019 were included and divided into two groups; NPWT with the lipidocolloid non-adherent dressing (group 1, experimental group, 19 patients) and NPWT only (group 2, control group, 19 patients). The condition of the wound was examined prior to NPWT application, at one week, and again at three weeks after application. No significant differences were found between groups for general characteristics, bacterial culture or photo analysis. However, when comparing groups based on the time of examination, there was a significant reduction of the wound size in group 1 (p = 0.001) but not in group 2 (p = 0.082). Therefore, the current study finds that using the lipidocolloid non-adherent dressing as a wound contact layer in NPWT stimulates healing by shrinking the size of the pressure ulcer wound.

show abstract

Selected physical medicine interventions in the treatment of diabetic foot syndrome

Cited by 11 publications

References 26 publications

Evaluation of Oxidative Stress in Patients with Difficult-to-Heal Skin Wounds Treated with Hyperbaric Oxygen

Evaluation of Oxidative Stress in Patients with Difficult-to-Heal Skin Wounds Treated with Hyperbaric Oxygen

Patient-Reported Outcome Measures for Patients with Diabetes Mellitus Associated with Foot and Ankle Pathologies: A Systematic Review

A Prospective Randomized Study: The Usefulness and Efficacy of Negative Pressure Wound Therapy with Lipidocolloid Polyester Mesh Compared to Traditional Negative Pressure Wound Therapy for Treatment of Pressure Ulcers

Contact Info

Product

Resources

About