Segmented heterochromia in black scalp hair associated with iron-deficiency anemia. Canities segmentata sideropaenica

Sato, S.

doi:10.1001/archderm.125.4.531

Cited by 10 publications

(12 citation statements)

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“…Segmented heterochromia in scalp hair refers to a hair condition resulting in alternating dark and light segments, which predominantly occurs in patients with iron-deficiency anaemia (1,2). Here, we demonstrate a single hair shaft presenting with alternating black and white bands, which suggests unstable follicular melanocyte viability or a transient interruption of follicular melanogenesis, without any remarkable underlying conditions.…”

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confidence: 75%

Segmented Heterochromia in a Single Scalp Hair

Cho¹,

Zheng²,

Kim³

et al. 2014

Acta Derm Venerol

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confidence: 75%

Segmented Heterochromia in a Single Scalp Hair

Cho¹,

Zheng²,

Kim³

et al. 2014

Acta Derm Venerol

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“…[1] There has been a case report of 15-year-old Japanese girl who has segmented heterochromic hair in association with iron deficiency anemia. [22] Her melanin content recovered after iron supplementation. It has been shown that iron affects melanogenesis, for example, in the rearrangement of dopachrome to 5, 6 – dihydroxyindoles and the oxidative polymerization of the 5, 6 – dihydroxyindoles to melanin pigments.…”

Section: Discussionmentioning

confidence: 99%

Epidemiological and investigative study of premature graying of hair in higher secondary and pre-university school children

et al. 2013

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Background:Hair pigmentation is one of the most conspicuous phenotypes in humans ranging from black, brown, and blonde to red. Premature graying of hair occurs more commonly without any underlying pathology but is said to be inherited in autosomal dominant pattern. Premature graying has been shown to be associated with a few of the autoimmune disorders. A role for environmental factors and nutritional deficiencies has also been postulated. However, to date the exact etiology of premature graying has not been established.Aim:The objective of our study was to conduct an epidemiological and investigative study of premature graying of hair in higher secondary and pre-university school children of the semi-urban area.Materials and Methods:A total of 35 cases and controls were investigated for various parameter such as Hemoglobin, total iron binding capacity, serum ferritin (S. Ferritin), serum calcium (S. Ca), serum iron (S. Iron), vitamin B12, and vitamin D3 after taking informed consent. Epidemiological and investigations correlation was established using the Chi-square and Mann Whitney test and P < 0.05 values were considered significant.Result:Among the various laboratory parameters S. Ca, S. Ferritin and vitamin D3 were low in patients with premature graying of hair. There was significant high number of vitamin D3 deficient and insufficient among the cases compared to the controls.Conclusion:According to our study S. Ca, S. Ferritin, vitamin D3 may play a role in premature graying of hair in our society.

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“…It is known to be associated with iron deficiency anemia. 1 Only three cases of the disease have been reported in Japan. [1][2][3] We report a case of segmented heterochromia of scalp hair in an 11-yearold boy.…”

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confidence: 99%

“…Estimates have suggested the frequency is approximately 1 case of cancer per 1000 gestations. 1 Placental metastasis from maternal cancer is even rarer. Although it constitutes only 8% of malignant tumors occurring with pregnancy, melanoma is the most common type of cancer to metastasize to the placenta.…”

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confidence: 99%