Segmentectomy versus lobectomy in early non‐small cell lung cancer of 2 cm or less in size: A population‐based study

Abstract

Equivalent OS and LCSS were demonstrated in patients with primary NSCLC of 20 mm or less without lymph node or distant metastasis.

Contemporary Concise Review 2018: Lung cancer and pleural disease

“…One such study published in this journal, a retrospective observational review of the Surveillance, Epidemiology, and End Results (SEER) cancer registry, found no significant difference in the 5‐year overall survival rates of 15 358 patients with primary NSCLC ≤ 20 mm, N0, treated with either lobectomy or anatomical segmentectomy (76% vs 74.4%, P = NS) . Elderly patients were more likely to have undergone segmentectomy, with a subgroup analysis of those >75 years old, demonstrating comparable overall and lung cancer specific survival rates compared with lobectomy.…”

Towards lung preservation in curative surgical treatment of early stage non‐small cell lung cancer

“… and a National Cancer Data Base analysis by Khullar et al ., Moon et al . in their recent publication in Respirology applied a slightly different approach to their SEER registry analysis . The time frame overlapped with Dai et al .’s paper, ranging from 2000 to 2014.…”

“…The results from Moon et al . add another layer of complexity to the limited resection vs lobectomy debate.…”

“…Due to the differences in these two analyses, as well as conflicting results from a meta-analysis by Bedetti et al 10 and a National Cancer Data Base analysis by Khullar et al, 11 Moon et al in their recent publication in Respirology applied a slightly different approach to their SEER registry analysis. 12 12 were careful to only examine the effect of segmentectomy vs lobectomy. Their results showed that segmentectomy for T ≤ 20 mm has similar overall survival and lung-cancer-specific survival compared to lobectomy despite showing a trend favouring lobectomy for lung-cancer-specific survival (P = 0.054).…”

“…In the age group above75 years, overall survival and lungcancer-specific survival were equivalent in both groups, which supported previous study results. 13 The results from Moon et al 12 add another layer of complexity to the limited resection vs lobectomy debate. Furthermore, Nishio et al showed that anatomical considerations as well as the consolidation to tumour ratio of greater than 0.5 are further important factors affecting recurrence rates.…”