Abstract:Darier's disease is a rare autosomal dominant genodermatosis. It has an estimated
prevalence of 1 in 55,000 to 100,000 individuals, regardless of gender. It is
characterized by multiple keratotic papules on the seborrheic areas of the trunk,
scalp, forehead and flexures, and the clinical picture is worsened by heat, sun
exposure, perspiration and mechanical trauma. Histopathology observed loss of
epithelial adhesion and abnormal keratinization. About 10% of cases present in the
localized form of the disease. W…
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