Sedation for fibreoptic bronchoscopy: comparison of alfentanil with papaveretum and diazepam

Webb, Ashley; Doherty, J.F.; Chester, Michael R.; Cummin, A.R.C.; Woodhead, M.; Nanson, Eric M.; Flack, S.T.; Millard, F. J. C.

doi:10.1016/s0954-6111(89)80034-4

Cited by 33 publications

(21 citation statements)

References 7 publications

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“…It is worth noting that it is now appreciated that oxygen desaturation during invasive endoscopic procedures is a common phenomenon, both with [9,35] and without oxygen supplementation [31]. This observation emphasises the importance of standard pulse oximetry and oxygen supplementation during flexible bronchoscopy, as stated in the British Thoracic Society guidelines [1].…”

Section: Clinical Practice D Stolz Et Almentioning

confidence: 99%

“…We hypothesise that these findings can be explained by the amnesic effect of midazolam. According to several previous studies, the wake-up time for combined sedation with an opiate and a benzodiazepine is 35-60 min and discharge time 75-120 min after the procedure [30][31][32]. Alternatively, propofol might have a shorter or less potent effect on the cough reflex than the combination of midazolam and hydrocodone [33,34].…”

Section: Clinical Practice D Stolz Et Almentioning

confidence: 99%

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Propofol versus combined sedation in flexible bronchoscopy: a randomised non-inferiority trial

Stolz¹,

Kurer²,

Meyer³

et al. 2009

European Respiratory Journal

109

115

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Combined sedation with a benzodiazepine and an opiate has been proposed as standard sedation for bronchoscopy. Propofol is a sedative-hypnotic with a rapid onset of action and fast recovery time, but carries the potential risk of respiratory failure.Consecutive patients (n5200) were randomly allocated to receive either the combination midazolam and hydrocodone or intravenous propofol. The primary end-points were the mean lowest arterial oxygen saturation during bronchoscopy and the readiness-for-discharge score 1 h after the procedure.The mean lowest arterial oxygen saturation during bronchoscopy did not differ across treatment groups (p50.422), and the number of patients recording an arterial oxygen saturation of f90% on at least one occasion was similar in both groups (p50.273). The median (interquartile range) readiness-for-discharge score 1 h after the procedure was significantly higher in the propofol group than in the combined sedation group (8 (6-9) versus 7 (5-9); p50.035). Patients assigned propofol exhibited less tachycardia during bronchoscopy and for o1 h after the examination. Minor procedural complications were noted in 71 (35.5%) patients and exhibited a similar incidence in both treatment arms (p50.460).Propofol is as effective and safe as combined sedation in patients undergoing flexible bronchoscopy, thus representing an appealing option if timely discharge is a priority.

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Section: Clinical Practice D Stolz Et Almentioning

confidence: 99%

Section: Clinical Practice D Stolz Et Almentioning

confidence: 99%

Propofol versus combined sedation in flexible bronchoscopy: a randomised non-inferiority trial

Stolz¹,

Kurer²,

Meyer³

et al. 2009

European Respiratory Journal

109

115

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“…Seit der Einführung der fiberoptischen Bronchoskopie im Jahr 1969 wurde eine Vielzahl von unterschiedlichen Sedierungstechniken publiziert, die teilweise bei Erwachsenen eingesetzt werden [56,76,84,98], oder auch Techniken, die auf medikamentöse Sedierung verzichten [9,73]. Berichte über flexible Bronchoskopie bei Kindern, die nur mit lokaler Oberflächenanästhesie ohne medikamentöse Sedierung durchgeführt werden, sind selten und enthalten keine Hinweise auf aufgetretene Komplikationen [90].…”

Section: Anästhesiologische Technikunclassified

Anästhesiologisches Management zur Endoskopie der Atemwege bei Kindern

Machotta

2002

Der Anaesthesist

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We have developed a modern strategy for the anaesthetic management of the pediatric airway using anaesthetic drugs such as sevoflurane, propofol, mivacurium and remifentanil, together with new techniques including the laryngeal mask. This strategy provides optimal conditions for the examiner and maximum safety for the pediatric patient. The endoscopic investigation of pediatric airways has become important for the diagnosis and treatment of many pediatric diseases, and is often performed with the support of a pediatric anaesthetist. Important indications include acute and chronic stridor, chronic obstructive airway disease, mucoviscidosis and foreign body aspiration. The best and safest techniques are outlined depending on the clinical situation, and the most frequent complications are discussed, e.g. hypoxaemia, respiratory arrest, laryngospasm, bronchial obstruction, pneumothorax and overdosing of local anaesthetic agents.

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“…Solunum yollan hastalıklarının tanısı ve tedavisinde bronkoskopi çok önemli bir tekniktir. İşlem sırasında hastanın rahat olması, trakeobronşial s'ekresyonunun ve vazovagal irritasyonunun minimal olması, öksürüğün giderilmesi intravenöz anestezik seçiminde özellikle dikkat edilmesi gereken noktalardır (13).…”

Section: Bulgularunclassified

Taniş Al Bronkoskopi̇k Gi̇ri̇şi̇mlerde Uygulanan Alfentani̇l Ve Propofolün Karşilaştirilmasi

Yeşim;TUTAR¹

1994

Ankara Üniversitesi Tıp Fakültesi Mecmuası

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Sedation for fibreoptic bronchoscopy: comparison of alfentanil with papaveretum and diazepam

Cited by 33 publications

References 7 publications

Propofol versus combined sedation in flexible bronchoscopy: a randomised non-inferiority trial

Propofol versus combined sedation in flexible bronchoscopy: a randomised non-inferiority trial

Anästhesiologisches Management zur Endoskopie der Atemwege bei Kindern

Taniş Al Bronkoskopi̇k Gi̇ri̇şi̇mlerde Uygulanan Alfentani̇l Ve Propofolün Karşilaştirilmasi

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