Secretory Cells in the Middle Ear Mucosa of the Guinea Pig: Cytochemical and Ultrastructural Study

Studies on the production of middle-ear effusion in the experimental animal

“…The cytological picture of the effusions and the histology of the mucosal lining presented in this preliminary report suggest that serous and mucous secretion is derived from secretory cells present in the epithelial layer. Secretory granules have been reported in the surface epithelium in health and disease on ultra-microscopy (Hilding, 1957;Hussl and Lim, 1969;Lime?al, 1967;Lim and Hussl, 1970;Lim andBirck, 1971;Kaneko and Paparella, 1971a and b;Hentzer, 1972). The hyperplasia of the epithelial layer and the thickening of the lamina propria in these experiments were similar to the features described by Senturia et al (1962).…”

Cilia distribution and polarity in the epithelial lining of the mouse middle ear cavity

“…5c). It is noted that previous studies have reported various characterizations of secretory cells in the middle ear epithelium, including Goblet cells and dark granulated cells5960. Moreover, Keratin 5 is also expressed in the non-ciliated squamous epithelial cells in the middle ear (Fig.…”

Sulfated glycopeptides from middle ear effusions of secretory otitis media.

“…Many investigators have studied secretory otitis media by histological and histochemical procedures (Henzer 1972;Hussl and Lim 1969). There have been, however, only a few biochemical studies of secretory otitis media (Juhn et al 1971;Vered et al 1972).…”