Secondary Metabolites of Medicinal Plants

Improving the bioactivity of water‐soluble alfalfa saponins using biotransformation

“…Meanwhile, the positive results of UHPLC–QTOF/MS and quantitative analysis demonstrated the reliability of the findings. The saponins MAG1, MAGA, and ZAGA, which are natural products found in the present study, were distributed among Medicago species (Singh & Sharma, 2020), with data available. The most effective allelochemical in alfalfa was MA, which had a broad and strong antimicrobial activity.…”

A phylogenetic evaluation of non‐random medicinal plants selection around an African biosphere reserve

“…To obtain the secondary compound richness for each family, we counted the number of bioactive compounds per family using the literature (Singh & Sharma, 2020). To test whether overutilised families are the most available families in the region, if they are the richest in secondary compounds, or if they are the most versatile (meaning they have the highest use value), we developed a generalized linear model with a binomial error distribution.…”

Biotechnological Approaches to Producing Natural Antioxidants: Anti-Ageing and Skin Longevity Prospects

“…At the same time, cells are exposed to high concentrations of ions to neutralize the undesirable impact on cell metabolism. This strategy has attracted scientists and researchers worldwide as it allows for the increase in cell viability and stability of the bioactive compounds produced, in addition to the increase in the production of desirable molecules [ 148 ]. For cell entrapment or immobilization, several chemicals, such as agarose, alginate, agar, and polyacrylamide combined with alginate, can be used as the gel matrix.…”

“…The beneficial effects of cell immobilization can be explained by the fact that the gel (polymer) matrix generates an appropriate diffusion gradient over the immobilized cells, which improves biochemical communication. Polymer matrices automatically trigger the establishment of cell aggregates, thereby reducing cells’ dependence on the culture media, resulting in a higher yield of PDBCs [ 148 ]. Although cell immobilization increases PDBC production, bioactive compounds are often entrapped and frequently stored within cell vacuoles.…”