Sebaceous glands within odontogenic cysts

Abstract

Aim: Sebaceous glands are rarely observed in odontogenic cysts whereas these structures are the histopathologic features of dermoid cysts. Dermoid cyst growth is slow and its biologic behaviour is silent; after the cyst is removed, recurrence is not observed. However, there are some developmental odontogenic cysts that have a local aggressive course and high levels of recurrence and sebaceous glands may present in these types of cyst. The aim of the study is to evaluate the histopathologic and clinical features of odontogenic cyst with sebaceous gland. Materials and Method: 14 odontogenic cysts with sebaceous glands were reported in the present study. Histopathological features, locations and numbers of sebaceous glands were evaluated. Histochemical (PAS) and immunohistochemical (S100 protein, Pan Cytokeratin, Cytokeratin 19 and EMA ) examinations were also performed. Results: In the present study, 14 patients, 9 (64%) male and 5 (36%) female with a mean age of 42 years were included. The cysts were located in the mandible of 10; while four of them were in the maxilla. All lesions were developmental odontogenic cysts. Microscopic evaluation revealed that sebaceous glands were only in the fibrotic cyst wall in 11 cases, in the intraepithelial location in 1 case and 2 cases showed three different sites as intraepithelial, subepithelial and wall. Conclusions: When the sebaceous glands are observed histopathologically, there is a tendency to diagnoisis as a dermoid cyst. Therefore, the differential diagnosis between odontogenic cyst with sebaceous glands and intraosseous dermoid cysts has great importance for management or different follow-up options.

Effect of an experimental green tea extract bleaching gel on the color changes of a composite resin

“…A recent study, regarding the bone loss in peri-implantitis, has demonstrated that this process can be the consequence of an oxidative stress and treating peri-implantitis with antioxidant herbal extract therapy can be a good choice [38].…”