Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.

Furtado, Fabiana Barcelos; Aquino, Francisco José Tôrres de; Nascimento, Evandro A.; Martins, Carla de Moura; Morais, Sérgio Antônio Lemos de; Chang, Roberto; Cunha, Luís Carlos Scalon; Leandro, Luís Fernando; Martins, Carlos Henrique Gomes; Martins, Mário Machado; Silva, Cláudio V. da; Machado, Fabricio; Oliveira, Alberto de

doi:10.3390/molecules19044560

Cited by 29 publications

(14 citation statements)

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“…24 Several fatty acids have been studied alone or in mixtures, and have shown antimicrobial and antifungal activities against different microorganisms. 25,26,27 Furthermore, these fatty acids have high commercial value.…”

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Volatile Compounds Obtained by the Hydrodistillation of Sugarcane Vinasse, a Residue from Ethanol Production

et al. 2017

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Sugarcane vinasse is the main by-product from ethanol production industries. Generated in large quantities, it is composed by water, inorganic and organic compounds and is extensively used as fertiliser in agriculture, promoting improvements in soil quality and crop yield. However, it has high pollution potential, as the high concentration of organic matter can lead to contamination of the soil and water, in addition to the risk of leaching of the mineral components. In the current study, the volatile components of vinasse were obtained by hydrodistillation using a Clevenger apparatus, then analysed by gas chromatography-mass spectrometry (GC-MS). A waxy material was obtained, and the GC-MS analysis indicated that vinasse is rich in fatty acids, alcohols and esters. The major components were phenylethyl alcohol (22.28%), myristic acid (17.45%), palmitic acid (15.81%), ethyl palmitate (8.99%) and hexadecanol (6.06%).

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Volatile Compounds Obtained by the Hydrodistillation of Sugarcane Vinasse, a Residue from Ethanol Production

et al. 2017

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“…44,57 The diterpene, phytol, although not abundant in B. campestris flower oil, may be an important contributor to the activity, since its role in antibacterial activity against oral microorganisms has already been described. 44,51 The EO of the B. campestris flower showed very strong to moderate activity against all the aerobic and anaerobic bacteria tested and could be a natural alternative in the prevention of diseases caused by oral microorganisms. The EO was also evaluated against some yeasts and the results are shown in Table 6.…”

Section: Resultsmentioning

confidence: 99%

“…40,41,46,55,56 The EO of the leaves of Inga laurina collected in rainy season, rich in hexadecanoic acid and phytol, showed significant antibacterial effect against aerobic and anaerobic oral bacteria. 51 Although many classes of metabolites may be present in EOs, the antimicrobial activity is also attributed to the presence of terpenes. 32,35,43,44,51,55 The monoterpenes linalool and α-terpineol have already demonstrated an effect against cariogenic bacteria, including S. mutans, the main etiological agent of dental caries.…”

Section: Resultsmentioning

confidence: 99%

“…51 Although many classes of metabolites may be present in EOs, the antimicrobial activity is also attributed to the presence of terpenes. 32,35,43,44,51,55 The monoterpenes linalool and α-terpineol have already demonstrated an effect against cariogenic bacteria, including S. mutans, the main etiological agent of dental caries. The non-terpene compound eugenol is considered a very promising antibacterial agent against these microorganisms.…”

Section: Resultsmentioning

confidence: 99%

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Chemical composition and antimicrobial activity of essential oil of flowers from Banisteriopsis campestris (A. Juss.) Little

et al. 2018

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The essential oil (EO) of the flowers from Banisteriopsis campestris was analysed by GC and GC-MS. Fatty acids were the most abundant class of compounds in the EO, followed by long-chain alkanes and oxygenated sesquiterpenes and monoterpenes. The main constituents were hexadecanoic acid (39.43 %), (E)-nerolidol (10.51 %), triacontane (9.08 %), heptacosane (5.49 %) and linalool (3.23 %). The antimicrobial activity of the EO was evaluated against aerobic and anaerobic oral bacteria and some yeasts by broth microdilution method. The EO inhibited the growth of all tested oral bacteria, showing strong activity against S. sanguinis with minimum inhibitory concentration (MIC) of 25 μg mL -1 . Considerable antibacterial activity was also observed for the anaerobes Porphyromonas gingivalis and Actinomyces naeslundii with MIC of 50 μg mL -1 . The EO of B. campestris flower showed moderate activity for S. mutans, S. mitis, A. actinomycetemcomitans and Fusobacterium nucleatum with MICs ranging between 200 and 400 μg mL -1 . The antifungal activity was evaluated against C. albicans, C. tropicalis and C. glabrata. The MIC results were above 3000 μg mL -1 , indicating inactivity against these yeasts. This study revealed that the OE of B. campestris flowers has promising antibacterial activity and this is the first report on its chemical composition and antimicrobial activity Resumo O óleo essencial (EO) das flores de Banisteriopsis campestris foi analisado por CG e GC-EM. Os ácidos graxos foram a classe de compostos mais abundantes no OE, seguidos por alcanos de cadeia longa, sesquiterpenos oxigenados e monoterpenos oxigenados. Os principais constituintes foram ácido palmítico (39,43 %), (E)-nerolidol (10,51 %), triacontano (9,08 %), heptacosano (5,49 %) e linalol (3,23 %). A atividade antimicrobiana do EO foi avaliada contra bactérias bucais aeróbias e anaeróbias e algumas espécies de Candida pelo método de microdiluição em caldo. O EO inibiu o crescimento de todas as bactérias bucais testadas, apresentando forte atividade contra a bactéria aeróbia S. sanguinis com concentração inibitória mínima (CIM) de 25 µg.mL -1 . Considerável atividade antibacteriana foi também observada para as bactérias anaeróbias Porphyromonas gingivalis e Actinomyces naeslundii com CIM de 50 µg.mL -1 . O EO da flor de B. campestris mostrou moderada atividade para S. mutans, S. mitis, A. actinomycetemcomitans e Fusobacterium nucleatum com concentrações inibitórias minimas entre 200 e 400 µg.mL -1 . A atividade antifúngica foi avaliada contra C. albicans, C. tropicalis e C. glabrata. Os resultados de MIC estiveram acima de 3.000 µg.mL -1 , indicando inatividade contra estas leveduras. Este estudo revelou que o OE das flores

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“…Although the exact mechanism of antibacterial activity of FFA is unknown, but it may be suggested that hydrophobic part is responsible for the activity by interacting with the hydrophobic parts of bacterial cell membrane. Moreover, elongated carbon chain length, presence of double bond and its position also affects antibacterial activity (Furtado et al 2014). Organic compounds having aromatic and phenolic moiety may attribute increased antimicrobial activity to the compound (Patnaik et al 2008).…”

Section: Discussionmentioning

confidence: 99%

GC-MS profile of antimicrobial and antioxidant fractions fromCordia rothiiroots

Khan

Firdous

Ahmad

et al. 2016

Pharmaceutical Biology

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Context: An ethnobotanical survey of Cordia rothii Roem. & Schult. (Boraginaceae) reveals it as a medicinal plant. Objective: Antimicrobial and antioxidant potential evaluation and identification of chemical constituents via GC-MS of C. rothii roots fractions. To the best of our knowledge, this is the first systematic investigation of the roots exploiting GC-MS. Materials and methods: Extraction and fractionation of C. rothii roots furnished various fractions using solvents of varying polarity, i.e., n-hexane, chloroform, ethyl acetate, acetone and methanol. In vitro antimicrobial and antioxidant screening was performed using disk diffusion and DPPH methods, respectively. MIC of active fractions was also determined using disk diffusion method. GC-MS was used to identify constituents which may be responsible for these activities. Results: Among various fractions from C. rothii roots, fraction KA-C showed strong antibacterial activity against 17 microorganisms tested, with MIC ranging from 250-31.25 lg/mL. Fractions KA-A, KM and KM-A exhibited significant antioxidant potential with EC 50 46.875 lg/mL, while fractions KEA-PE, KM-PE and KM-M were good with EC 50 93.750 lg/mL. Forty-five phytochemicals were identified in GC-MS studies including eight hydrocarbons, six free fatty acids, 11 fatty acids esters, two phenylpropanoids, four aromatics, four terpenoid quinones/hydroquinones, three triterpenes, four phytosterols, two hexose metabolites and a DNA base. Of these, 32 constituents have been reported for the first time from C. rothii, 24 from genus Cordia and 15 from Boraginaceae. Discussion and conclusion: Strong antibacterial and antioxidant potential of C. rothii roots may be due to the contribution of phytoconstituents identified through GC-MS studies.ARTICLE HISTORY

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Seasonal Variation of the Chemical Composition and Antimicrobial and Cytotoxic Activities of the Essential Oils from Inga laurina (Sw.) Willd.

Cited by 29 publications

References 44 publications

Volatile Compounds Obtained by the Hydrodistillation of Sugarcane Vinasse, a Residue from Ethanol Production

Volatile Compounds Obtained by the Hydrodistillation of Sugarcane Vinasse, a Residue from Ethanol Production

Chemical composition and antimicrobial activity of essential oil of flowers from Banisteriopsis campestris (A. Juss.) Little

GC-MS profile of antimicrobial and antioxidant fractions fromCordia rothiiroots

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