In ternary systems consisting of saturated and unsaturated lipids together with a sterol it is found that lateral phase separation into liquid ordered (lo) and disordered (ld) phases takes place. The phase behavior is critically dependent on the components with respect to the chain length, chain homogeneity, and the level of unsaturation in the lipids, and to the sterol structure. The phase separation is found to be strongly dependent on the ordering effect of the sterol on the lipid chains and on the solubil…
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