2011
DOI: 10.1590/s0104-11692011000600026
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Abstract: Infection with Group B Streptococcus (GBS) is considered an important public health problem. It is associated with: Neonatal sepsis, meningitis, pneumonia, neonatal death, septic abortion, chorioamnionitis, endometritis and other perinatal infections. The aim of this study was to determine the best screening strategy for GBS in pregnant women. foram favoráveis ao programa de screening universal para a redução da incidência de sepse neonatal. Pode-se concluir que evidências obtidas no estudo são sugestivas de … Show more

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Cited by 17 publications
(19 citation statements)
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“…The majority of studies on GBS screening compare the incidence of early onset infection in a period of screening against a historical control period (that is, risk based prevention) 74757685868788. Risk of bias is higher in these studies because participants in the two arms are not contemporaneous, so other differences between these periods may contribute.…”
Section: Uncertain Evidence On Screening Effectivenessmentioning
confidence: 99%
“…The majority of studies on GBS screening compare the incidence of early onset infection in a period of screening against a historical control period (that is, risk based prevention) 74757685868788. Risk of bias is higher in these studies because participants in the two arms are not contemporaneous, so other differences between these periods may contribute.…”
Section: Uncertain Evidence On Screening Effectivenessmentioning
confidence: 99%
“…Up to 30% of mothers positive in pregnancy may become negative by birth, and less than 1% of mothers colonised in labour have a baby with EOGBS, all of whom could be unnecessarily exposed to potential harms [ 13 , 7 ]. As observational evidence on universal GBS screening effectiveness is limited due to inherent biases [ 68 , 9 ], an RCT could inform on both the effectiveness and harms of screening and IAP treatment for neonatal GBS disease prevention.…”
Section: Discussionmentioning
confidence: 99%
“…In mehreren Metaanalysen wurde die Wirksamkeit der Prophylaxe von GBS Neugeborenensepsis durch Screening im Vergleich zur Prophylaxe aufgrund von vorliegenden Risikofaktoren überprüft. Hierbei zeigte sich eine Halbierung des Erkrankungsrisikos für die GBS Screening Strategie im Vergleich zur risikobasierten Strategie [16,28]. Somit erscheint es wahrscheinlich, dass die postulierte häufigere Durchführung des GBS Screenings einen wesentlichen Beitrag zum Inzidenzrückgang der EOS in Deutschland geleistet hat.…”
Section: Introductionunclassified