“…This might explain why mammography is a less accurate screening tool for our patients; considering the fact that higher breast density in younger age groups reduces mammography sensitivity and detection of microcalcifications (Foxcroft et al, 2004). Due to lack of enough evidences supporting effectiveness of mammography screening for women 40-49 years (Medical Advisory Secretariat., 2007), simple, realistic, particular, efficient and evidence based screening programs that correspond well with the pattern of BC in Iran should be established as a crucial part of our future strategies to reverse the increasing trend of disease (Mousavi et al, 2008;Porter., 2009). Our study therefore provides some complementary information on the age distribution, stage and nature of BC in a developing country that might help health care systems and physicians reorganize and implement strategies to improve preventive and therapeutic approaches to lower the burden of BC in these countries.…”