Screening for breast cancer: a review

Barriers to breast cancer screening in older women A review

“…Indeed, in one major European screening program, CBE was discontinued because of its perceived inadequacy in detecting cancer (43). Yet, others have spoken against abandoning CBE as a screening modality because there has been at least indirect evidence that it helps to reduce mortality at a greater rate than BSE (44) and because there have been estimates that 10% to 15% of cancerous tumors are missed by MAM, many of which are too large for detection by MAM and yet would be felt on physical examination (45).…”

Barriers to breast cancer screening in older women A review

“…Indeed, in one major European screening program, CBE was discontinued because of its perceived inadequacy in detecting cancer (43). Yet, others have spoken against abandoning CBE as a screening modality because there has been at least indirect evidence that it helps to reduce mortality at a greater rate than BSE (44) and because there have been estimates that 10% to 15% of cancerous tumors are missed by MAM, many of which are too large for detection by MAM and yet would be felt on physical examination (45).…”

The biology and natural history of breast cancer from the screening perspective

“…From a statistical point of view, this means that large study groups and long observation times are needed to accumulate enough events in order to give estimates of any eventual effect on mortality with reasonable statistical power. Point estimates of the effect of screening women under 50 years of age have hitherto been accompanied by wide confidence intervals, and longer follow-up periods have also given some evidence for an effect of screening in this age group [36].…”

Breast cancer in Canada: To screen or not to screen?

“…For years, the results of controlled studies indicated that mortality attributable to breast cancer could be reduced from 30 to 50y0 for up to 18 years after screening (Day and Chamberlain, 1988;Miller, 1988a;Dean, 1987, 1989). Now, the preliminary results of the multi-million dollar National Breast Screening Study (NBSS) conducted in Canada question the advisability of MA for women aged 40 to 49.…”

Barriers to breast cancer screening in older women A review

“…Indeed, in one major European screening program, CBE was discontinued because of its perceived inadequacy in detecting cancer (43). Yet, others have spoken against abandoning CBE as a screening modality because there has been at least indirect evidence that it helps to reduce mortality at a greater rate than BSE (44) and because there have been estimates that 10% to 15% of cancerous tumors are missed by MAM, many of which are too large for detection by MAM and yet would be felt on physical examination (45).…”

The biology and natural history of breast cancer from the screening perspective

“…From a statistical point of view, this means that large study groups and long observation times are needed to accumulate enough events in order to give estimates of any eventual effect on mortality with reasonable statistical power. Point estimates of the effect of screening women under 50 years of age have hitherto been accompanied by wide confidence intervals, and longer follow-up periods have also given some evidence for an effect of screening in this age group [36].…”

Breast cancer in Canada: To screen or not to screen?

“…For years, the results of controlled studies indicated that mortality attributable to breast cancer could be reduced from 30 to 50y0 for up to 18 years after screening (Day and Chamberlain, 1988;Miller, 1988a;Dean, 1987, 1989). Now, the preliminary results of the multi-million dollar National Breast Screening Study (NBSS) conducted in Canada question the advisability of MA for women aged 40 to 49.…”

Barriers to breast cancer screening in older women A review

“…Indeed, in one major European screening program, CBE was discontinued because of its perceived inadequacy in detecting cancer (43). Yet, others have spoken against abandoning CBE as a screening modality because there has been at least indirect evidence that it helps to reduce mortality at a greater rate than BSE (44) and because there have been estimates that 10% to 15% of cancerous tumors are missed by MAM, many of which are too large for detection by MAM and yet would be felt on physical examination (45).…”

The biology and natural history of breast cancer from the screening perspective

“…From a statistical point of view, this means that large study groups and long observation times are needed to accumulate enough events in order to give estimates of any eventual effect on mortality with reasonable statistical power. Point estimates of the effect of screening women under 50 years of age have hitherto been accompanied by wide confidence intervals, and longer follow-up periods have also given some evidence for an effect of screening in this age group [36].…”

Breast cancer in Canada: To screen or not to screen?

“…For years, the results of controlled studies indicated that mortality attributable to breast cancer could be reduced from 30 to 50y0 for up to 18 years after screening (Day and Chamberlain, 1988;Miller, 1988a;Dean, 1987, 1989). Now, the preliminary results of the multi-million dollar National Breast Screening Study (NBSS) conducted in Canada question the advisability of MA for women aged 40 to 49.…”