Scraping for human scabies. A better method for positive preparations

Muller, G.

doi:10.1001/archderm.107.1.70

Cited by 7 publications

(5 citation statements)

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“…18 To enhance the results, the groove done by the parasite can be opened with a fine needle and Muller oil or immersion oil is applied to bring the acarus at the surface. 19,20 A negative microscopic result does not exclude scabies. 12,21 Dermoscopic examination can identify skin burrows, mites (the 'delta' sign at the end of the burrow represents the anterior body of the adult female mite), 22 eggs and can orientate the site of skin scrapings.…”

Section: Diagnosismentioning

confidence: 99%

“…Definitive diagnosis is supported by a positive microscopic examination of skin scrapings which identifies mites, eggs or faecal pellets (‘scybala’) . To enhance the results, the groove done by the parasite can be opened with a fine needle and Muller oil or immersion oil is applied to bring the acarus at the surface . A negative microscopic result does not exclude scabies …”

Section: Diagnosismentioning

confidence: 99%

“…Dermoscopic examination can identify skin burrows, mites (the ‘delta’ sign at the end of the burrow represents the anterior body of the adult female mite), eggs and can orientate the site of skin scrapings . In sexually active patients, STI screening (including HIV test) is recommended {level of evidence Ib; grade A recommendation} …”

Section: Diagnosismentioning

confidence: 99%

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European guideline for the management of scabies

Sălăvăstru

Chosidow

Boffa

et al. 2017

Acad Dermatol Venereol

254

237

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Scabies is caused by Sarcoptes scabiei var. hominis. The disease can be sexually transmitted. Patients' main complaint is nocturnal itch. Disseminated, excoriated, erythematous papules are usually seen on the anterior trunk and limbs. Crusted scabies occurs in immunocompromised hosts and may be associated with reduced or absent pruritus. Recommended treatments are permethrin 5% cream, oral ivermectin and benzyl benzoate 25% lotion. Alternative treatments are malathion 0.5% aqueous lotion, ivermectin 1% lotion and sulphur 6-33% cream, ointment or lotion. Crusted scabies therapy requires a topical scabicide and oral ivermectin. Mass treatment of large populations with endemic disease can be performed with a single dose of ivermectin (200 micrograms/kg of bodyweight). Partner management needs a look-back period of 2 months. Screening for other STI is recommended. Patients and close contacts should avoid sexual contact until completion of treatment and should strictly observe personal hygiene rules when living in crowded spaces. Written information should be provided to suspected cases.

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Section: Diagnosismentioning

confidence: 99%

Section: Diagnosismentioning

confidence: 99%

See 1 more Smart Citation

European guideline for the management of scabies

Sălăvăstru

Chosidow

Boffa

et al. 2017

Acad Dermatol Venereol

254

237

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“…As a first step, an experienced dermatologist delineated clinically suspicious lesions. Skin scrapings for patients with suspected scabies were obtained from clinically suspected lesions by an experienced nurse specialist for microscopic examination and scabies PCR simultaneously [13]. The specimens were collected at 10~15 sites for all delineated lesions.…”

Section: Patients and Clinical Diagnosis Of Scabiesmentioning

confidence: 99%

Diagnostic value of the molecular detection of Sarcoptes scabiei from a skin scraping in patients with suspected scabies

et al. 2020

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Scabies is a highly contagious parasitic disease associated with long-term residence in nursing homes, and it is a public health burden worldwide. However, atypical skin manifestations are frequent and the widely used diagnostic test based on microscopic examinations has limited sensitivity. We evaluated the diagnostic value of polymerase chain reaction (PCR) from skin scraping in patients with suspected scabies. Adult patients with suspected scabies, unrelated diseases or healthy volunteers were enrolled at a tertiary hospital, in Seoul, South Korea, from December 2017 through October 2018. We classified participants based on the consensus criteria established by the International Alliance for the Control of Scabies in 2018; confirmed (microscopic mite detection), clinical (scabies burrow or typical lesions with two history features including itch and close contact with scabies patients), suspected scabies (typical lesion with one history feature or atypical lesion with two history features), or no scabies. PCR was performed on the skin scrapings to target the cytochrome c oxidase subunit 1 (cox1) gene of Sarcoptes scabiei. A total of 47 participants, 33 with suspected scabies, 10 with unrelated diseases, and 4 healthy volunteers were enrolled. Of the 33 patients, 22 were classified as confirmed scabies, 2 as clinical scabies, 6 as suspected scabies, and 3 as no scabies. The sensitivities of the microscopic examination were 100%, 92%, and 73% in confirmed scabies; confirmed and clinical scabies; and confirmed, clinical, and suspected scabies, respectively (p = 0.006). The sensitivities of PCR were 86%, 83%, and 80% in confirmed scabies; confirmed and clinical scabies; and confirmed, clinical, and suspected scabies, respectively (p = 0.59). The specificity of the scabies PCR in the no scabies control was 100% (95% CI = 80-100).PCR testing for scabies may be helpful in the improvement of sensitivity for the diagnosis of scabies by clinical criteria.

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“…Le dermatoscope est un outil précieux, très sensible, qui permet l'examen des sillons et d'identifier le " signe du deltaplane " (triangle noir à la fin du sillon correspondant au corps antérieur du sarcopte) qui guidera le prélèvement cutané 25,26 (figure 3). Le test à l'encre de chine déposée sur des sites suspects révélant les terriers comme une ligne ondulée, est de moins en moins utilisé 27,28 .…”

Section: Diagnosticunclassified

Management of scabies in 2019

Goldberg¹,

André²,

Richert³

2019

Rev Med Brux

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La gale est une dermatose infectieuse transmise par l'ectoparasite Sarcoptes scabiei var. hominis. Elle reste encore fréquente et affecte les patients indépendamment de leur niveau socio-économique et de l'hygiène. Le diagnostic est essentiellement clinique. Un prurit généralisé à recrudescence nocturne et des manifestations cutanées de topographie particulière sont hautement évocateurs. La présentation clinique varie avec l'âge. Le diagnostic précoce est impératif pour limiter la transmission. Les traitements individuels et familiaux font appel aux traitements topiques (perméthrine ; benzoate de benzyle). L'ivermectine orale est indiquée en cas d'épidémie institutionnelle (homes, hôpitaux et prisons). Pour espérer un contrôle durable de l'infection, de nouvelles méthodes diagnostiques et des thérapeutiques simples, précises, efficaces et peu coûteuses sont nécessaires.

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Scraping for human scabies. A better method for positive preparations

Cited by 7 publications

References 0 publications

European guideline for the management of scabies

European guideline for the management of scabies

Diagnostic value of the molecular detection of Sarcoptes scabiei from a skin scraping in patients with suspected scabies

Management of scabies in 2019

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