<scp>Non‐Mendelian</scp> inheritance of gene amplification‐based resistance to glyphosate in <scp><i>Hordeum glaucum</i></scp> (barley grass) from <scp>South Australia</scp>

Adu-Yeboah, Patricia; Malone, Jenna; Gill, Gurjeet; Preston, Christopher

doi:10.1002/ps.6518

Cited by 3 publications

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

Perspectives on gene copy number variation and pesticide resistance

Heckel

2021

Pest Management Science

View full text Add to dashboard Cite

Although the generation of evolutionary diversity by gene duplication has long been known, the implications for pesticide resistance are just now beginning to be appreciated. A few examples will be cited to illustrate the point that there are many variations on the theme that gene duplication does not follow a set pattern. Transposable elements may facilitate the process but the mechanistic details are obscure and unpredictable. New developments in DNA sequencing technology and genome assembly promise to reveal more examples, yet care must be taken in interpreting the results of transcriptome and genome assemblies and independent means of validation are important. Once a specific gene family is identified, special methods generally must be used to avoid underestimating population polymorphisms and being trapped in preconceptions about the simplicity of the process. © 2021 The Author. Pest Management Science published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.

show abstract

Perspectives on gene copy number variation and pesticide resistance

Heckel

2021

Pest Management Science

View full text Add to dashboard Cite

show abstract

Frequent spontaneous structural rearrangements promote rapid genome diversification in a Brassica napus F1 generation

Orantes-Bonilla

Makhoul

Lee

et al. 2022

Preprint

View full text Add to dashboard Cite

In F1 offspring from a cross between two Brassica napus plants of synthetic and natural origin, we demonstrate the occurrence of novel transgenerational structural genome variants. Long read sequencing in twelve F1 sister plants revealed five large-scale structural rearrangements where both parents carried different homozygous alleles but the heterozygous F1 genomes were not identical heterozygotes as expected. Such spontaneous rearrangements were part of homoeologous exchanges or segmental deletions and were identified in different, individual F1 plants. The variants caused deletions, gene copy-number variations, diverging methylation patterns and other structural changes in large numbers of genes and may have been causal for unexpected phenotypic variation between individual F1 sister plants, for example strong divergence of plant height and leaf area. This example suggests that the spontaneous occurrence of transgenerational de novo structural rearrangements could be a feasible model for how allopolyploid crops can rapidly overcome intense allopolyploidization bottlenecks to re-expand their genetic diversity for ecogeographical expansion and human selection. The strong implications of these findings for potentially widespread gene loss or neofunctionalization in individual polyploid plants also raises the intriguing possibility that natural genome restructuring in polyploid plants may have a considerably more drastic impact on genetic diversity in agricultural ecosystems than extremely precise, biotechnological genome modifications.

show abstract

Frequent spontaneous structural rearrangements promote rapid genome diversification in a Brassica napus F1 generation

et al. 2022

View full text Add to dashboard Cite

In a cross between two homozygous Brassica napus plants of synthetic and natural origin, we demonstrate that novel structural genome variants from the synthetic parent cause immediate genome diversification among F1 offspring. Long read sequencing in twelve F1 sister plants revealed five large-scale structural rearrangements where both parents carried different homozygous alleles but the heterozygous F1 genomes were not identical heterozygotes as expected. Such spontaneous rearrangements were part of homoeologous exchanges or segmental deletions and were identified in different, individual F1 plants. The variants caused deletions, gene copy-number variations, diverging methylation patterns and other structural changes in large numbers of genes and may have been causal for unexpected phenotypic variation between individual F1 sister plants, for example strong divergence of plant height and leaf area. This example supports the hypothesis that spontaneous de novo structural rearrangements after de novo polyploidization can rapidly overcome intense allopolyploidization bottlenecks to re-expand crops genetic diversity for ecogeographical expansion and human selection. The findings imply that natural genome restructuring in allopolyploid plants from interspecific hybridization, a common approach in plant breeding, can have a considerably more drastic impact on genetic diversity in agricultural ecosystems than extremely precise, biotechnological genome modifications.

show abstract

Non‐Mendelian inheritance of gene amplification‐based resistance to glyphosate in Hordeum glaucum (barley grass) from South Australia

Cited by 3 publications

References 39 publications

Perspectives on gene copy number variation and pesticide resistance

Perspectives on gene copy number variation and pesticide resistance

Frequent spontaneous structural rearrangements promote rapid genome diversification in a Brassica napus F1 generation

Frequent spontaneous structural rearrangements promote rapid genome diversification in a Brassica napus F1 generation

Contact Info

Product

Resources

About