KCC‐1‐nPr‐NH‐Argas an efficient organo‐nanocatalyst for the green synthesis of 1,8‐dioxo decahydroacridine derivatives

Abstract

In the present work, an innovative biocompatible heterogeneous organo-nanocatalyst is prepared based on the grafting of arginine amino acid on the channels and pores of dendritic fibrous nano silica. The designed organo-nanocatalyst (KCC-1-nPr-NH-Arg) was characterized by using field emission scanning electron microscopy, Fourier transform infrared spectroscopy, energy dispersive X-ray spectroscopy, map analysis, and adsorption/desorption instruments. The results of analysis show that the engineered catalyst has uniform fibrous spheres and dendritic structure with high surface area (104.9 m 2 /g) and great pore volume (0.83 cm 3 g À1 ). Because of exceptional dendritic structure of the prepared organo-nanocatalyst, the active sites are available and the difusion and adsorption capacity of the reagents and products increase in the pores and channels of the catalyst. Hence, KCC-1-nPr-NH-Arg was used as an capable heterogeneous basic nanocatalyst in the synthesis of 1,8-dioxo decahydroacridine derivatives from the one-pot four component reactions of aromatic aldehydes, dimedone, and ammonium acetate in solvent free conditions with shorter reaction times (13-35 minutes) and higher yields (94%-98%) in evaluation with other reported works. It is expected that the green organo-nanocatalyst can be used to synthesize other organic compounds.