<scp>HCV</scp> hotline facilitates Hepatitis C elimination during the <scp>COVID</scp>‐19 pandemic

Hartl, Lukas; Jachs, Mathias; Bauer, Dávid; Simbrunner, Benedikt; Chromy, David; Binter, Teresa; Steininger, Lisa; Schwarz, Christoph; Schwarz, Michael; Burghart, Lukas; Straßl, Robert; Trauner, Michael; Gschwantler, Michael; Mandorfer, Mattias; Reiberger, Thomas

doi:10.1111/jvh.13746

Cited by 6 publications

(3 citation statements)

References 43 publications

(134 reference statements)

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“…We read with great interest the manuscript published by Hartl et al 1 showing that efforts for hepatitis C virus (HCV) elimination can be made even during infectious disease outbreaks. Recently,…”

Section: Monkeypox Outbreak As An Opportunity To Identify New Cases O...mentioning

confidence: 99%

Monkeypox outbreak as an opportunity to identify new cases of HCV infection in limited resource settings

Perazzo

Silva

Coutinho

et al. 2022

Journal of Viral Hepatitis

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Section: Monkeypox Outbreak As An Opportunity To Identify New Cases O...mentioning

confidence: 99%

Monkeypox outbreak as an opportunity to identify new cases of HCV infection in limited resource settings

Perazzo

Silva

Coutinho

et al. 2022

Journal of Viral Hepatitis

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“…To our knowledge, this is the first evaluation of a program which referred patients directly to a remote online evaluation system (HCV e-consult DTT program) with subsequent successful HCV treatment initiation and completion by midlevel providers, highlighting a potential model for other integrated healthcare systems. There exist other telehealth programs that have been demonstrated to be effective for HCV treatment 12 – 15 . Of particular note, at the VA, one study found that sites that offered video conferencing between primary care providers and people living with HCV as part of the HCV VA-ECHO program had higher treatment initiation rates than sites that did not offer this 16 .…”

Section: Discussionmentioning

confidence: 99%

Evaluation of and implications for a novel hepatitis C e-consult direct-to-treatment pilot program

Mohtashemi,

Teng,

Benhammou

et al. 2023

Sci Rep

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A Hepatitis C (HCV) e-Consult Direct-To-Treatment (DTT) program managed by midlevel providers was developed at the Veteran Affairs Greater Los Angeles Healthcare System (VAGLAHS) which provided remote referral and, in some, remote management of HCV. DTT patients were more likely to be initiated on HCV treatment compared to standard of care (SOC), lending support for similar programs of remote engagement in HCV care.

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“…To remove information and treatment barriers, a physician-based hotline operated by specialists at the viral hepatitis clinic of the Medical University of Vienna offers a low-barrier tool for communication and linkage to care [ 15 , 19 ]. In 2019, 79 antiviral therapies with an SVR4 rate of 98.0% were initiated via this “HepC Phone” [ 15 ].…”

Section: Introductionmentioning

confidence: 99%

ELIMINATE: a PCR record-based macroelimination project for systematic recall of HCV-RNA-positive persons in Austria

Schwarz,

Bauer,

Dorn

et al. 2023

Wien Klin Wochenschr

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Summary Background and aims Micro-elimination projects targeted to specific hepatitis C virus (HCV) risk populations have been successful. Systematic identification of persons with HCV viremia, regardless of risk group, based on already available laboratory records may represent an effective macroelimination approach to achieve global HCV elimination. Methods Persons with a last positive HCV-RNA PCR result between 2008–2020 in the reference virology laboratories in eastern Austria were identified. First, (i) we described their demographic characteristics, (ii) we systematically recalled persons to the respective centers and (iii) started antiviral treatment if HCV-RNA viremia was confirmed, and (iv) recorded sustained virologic response (SVR). This interim report includes the preliminary results from 8 participating centers. Results During the study period 22,682 persons underwent HCV-RNA PCR testing, 11,216 (49.4%) were positive at any point in time, and 6006 (26.5%) showed detectable HCV-RNA at the last PCR test, suggesting ongoing HCV viremia. At the time of this interim report, 2546/6006 HCV-RNA PCR(+) persons were evaluated: 443/2546 (17.4%) had died, 852/2546 (33.5%) had invalid contact data, and 547/2546 (21.5%) had achieved SVR between data retrieval and recall. Contact could be established in 236/704 (33.5%) of the remaining target population with 97/236 (41.1%) presenting at the clinic for treatment evaluation. Ultimately, 71/236 (30.1%) started antiviral treatment and SVR was documented in 47/71 (66.2%). Conclusion This ELIMINATE project based on systematic assessment of HCV-RNA PCR-records, identified 6006 persons with potential persisting HCV viremia. Invalid contact data and missed visits for treatment evaluation were the main barriers towards HCV elimination within this project. Importantly, many subjects with HCV viremia lost to follow-up were successfully linked to care and started antiviral treatment.

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HCV hotline facilitates Hepatitis C elimination during the COVID‐19 pandemic

Abstract: This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.

Cited by 6 publications

References 43 publications

Monkeypox outbreak as an opportunity to identify new cases of HCV infection in limited resource settings

Monkeypox outbreak as an opportunity to identify new cases of HCV infection in limited resource settings

Evaluation of and implications for a novel hepatitis C e-consult direct-to-treatment pilot program

ELIMINATE: a PCR record-based macroelimination project for systematic recall of HCV-RNA-positive persons in Austria

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