Scotoma and fixation patterns using scanning laser ophthalmoscope microperimetry in patients with macular dystrophy

Mori, Fumihiko; Ishiko, Satoshi; Kitaya, Norihiko; Takamiya, Akira; Satô, Eiichi; Hikichi, Taiichi; Yoshida, Akitoshi

doi:10.1016/s0002-9394(01)01216-8

Cited by 52 publications

(35 citation statements)

References 7 publications

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“…1,[13][14][15] For example, a quick fixation test might avoid the application of laser photocoagulation to fixation points, which could cause a sudden visual acuity decrease. 16 Detection of PRL also might be important during the preoperative examination for submacular surgery.…”

Section: Discussionmentioning

confidence: 99%

A Microperimeter That Provides Fixation Pattern and Retinal Sensitivity Measurement

et al. 2006

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Section: Discussionmentioning

confidence: 99%

A Microperimeter That Provides Fixation Pattern and Retinal Sensitivity Measurement

et al. 2006

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“…Previous studies using SLO Microperimetry in patients with STGD have shown that most patients develop a central absolute scotoma and establish eccentric fixation [24,25,28,29].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of macular abnormalities in Stargardt’s disease using optical coherence tomography and scanning laser ophthalmoscope microperimetry

Berisha

Feke

Aliyeva

et al. 2008

Graefes Arch Clin Exp Ophthalmol

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“…9 Interestingly, the fixation in patients with BVD, although eccentric (Group 3), was stable in three out of eight eyes, relatively unstable in four, and unstable in one eye only. This may be due to the fact that in patients with Stargardt's disease, the damage between the eyes was relatively symmetric (VA: 0.01 o.u.…”

Section: Discussionmentioning

confidence: 79%

“…8 The type of scotoma may affect shifting of fixation points and possibly result in a difference in visual acuity. 9 Fundus autofluorescence imaging (AF) provides new information regarding the morphologic status of RPE by giving information about content and spatial distribution of lipofuscin in eyes with retinal dystrophies. 10,11 Lipofuscin accumulation is common in many retinal dystrophies, showing different patterns of distribution on the patient's fundus.…”

Section: Introductionmentioning

confidence: 99%

Mapping of central visual function by microperimetry and autofluorescence in patients with Best's vitelliform dystrophy

Jarc-Vidmar

Popović

Hawlina

2005

Eye

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Purpose To evaluate retinal sensitivity and fixation patterns in patients with Best's dystrophy by microperimetry (MP) and to correlate the results with static perimetry and retinal morphology seen by autofluorescence (AF). Methods Central 101 visual fields in 11 patients with Best's dystrophy (VA: 0.570.38) were recorded by the Octopus M2 TOP program and by MP (MP1, Nidek Technologies). AF was recorded by HRA (Heidelberg Engineering). Results High correlation (R ¼ 0.75, À0.76, À0.48) was found between static perimetry (MS, MD and CLV indices) and MP. Based on MP and AF results, three groups of patients were formed. Patients in the first two groups fixated inside the central nonuniform hypoand hyperfluorescent AF ring area, next to relative (Group 1) or absolute scotoma (Group 2). Inner parts of the retina close to the fovea were most affected, whereas regions closer to the periphery of the 101 visual field showed near normal function. As the disease progressed, there was an evident shift of fixation to preferential retinal locus (PRL) in eight eyes with visual acuity 0.2 or less (Group 3). Fixation shift was superior in four eyes, temporal in two eyes, and nasal in two eyes. Conclusion MP enabled a highly sensitive topographic monitoring of retinal function, showing central or pericentral fixation in the early stages, until loss of central function, in eyes with VA 0.2 or less, caused evident shift of fixation to PRL. PRL was never situated inside the central uniform hypofluorescent area, but corresponded with the hyperfluorescent ring seen with AF imaging.

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Scotoma and fixation patterns using scanning laser ophthalmoscope microperimetry in patients with macular dystrophy

Cited by 52 publications

References 7 publications

A Microperimeter That Provides Fixation Pattern and Retinal Sensitivity Measurement

A Microperimeter That Provides Fixation Pattern and Retinal Sensitivity Measurement

Evaluation of macular abnormalities in Stargardt’s disease using optical coherence tomography and scanning laser ophthalmoscope microperimetry

Mapping of central visual function by microperimetry and autofluorescence in patients with Best's vitelliform dystrophy

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