Skeletal Radiol

2020

DOI: 10.1007/s00256-020-03644-0

|View full text |Cite

|

Sign up to set email alerts

|

Sclerotic bone lesions caused by non-infectious and non-neoplastic diseases: a review of the imaging and clinicopathologic findings

¹

,

²

,

³

et al.

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Discussion2

Citation Types

Supporting

0

Mentioning

3

Contrasting

0

Year Published

2022

2022

2024

2024

Publication Types

Select...

Article5

Book1

Relationship

Self Cite0

Independent6

Authors

Journals

Cited by 9 publications

(3 citation statements)

References 65 publications

Supporting

0

Mentioning

3

Contrasting

0

Order By: Relevance

“…Sometimes the callus is visible, but the fracture line itself cannot be seen (Devas & Sweetnam, 1956). The differential diagnosis for a stress fracture in skeletal samples may include neoplasm, infection, and sclerotic bone lesions of non‐infectious and non‐neoplastic origin (Gulati et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

The hazards of the pastoralist lifestyle: Evidence from postcranial fractures in Middle Bronze and Early Iron Age populations of the Forest‐Steppe Altai, Russia

Tur,

Svyatko,

Rykun

et al. 2024

Intl J of Osteoarchaeology

View full text Add to dashboard Cite

A global comparison has shown that subsistence‐specific practices influenced the risk of postcranial fractures in prehistoric hunter‐gatherers and agriculturalists. Much less is known about pastoralists in this regard. The aim of the study was to investigate the prevalence and patterns of postcranial injuries of herders in the Forest‐Steppe Altai, Russia. Skeletal samples associated with the Andronovo Culture of the Middle Bronze Age, and Staroaleyka and Kamen Cultures of the Early Iron Age were studied. Long bones of 595 adults were examined for evidence of antemortem and perimortem injuries. Fracture frequencies were calculated per individual and per skeletal element, and the differences were evaluated statistically. While assessing per individual, the relative risk with a 95% confidence interval was calculated as well. All of the observed fractures were healed. This study suggests that pastoralists sustained not only traumatic, but also stress injuries. There were sex‐related differences in the rates, patterns, and location of the injuries. In the males, the main reason of fractures could have been high‐velocity incidents during horseback riding and using horse‐drawn vehicles. In the females, the majority of the injuries were possibly associated with accidents when walking (short falls and twists of ankle) and milking. Females of the Staroaleyka Culture sustained fractures of the limb bones significantly more often than those of the Kamen Culture, probably as a result of differences in their daily activities. In terms of the total fracture rates, the Forest‐Steppe Altai pastoralists and their neighbors seem to have surpassed low‐intensity agriculturalists but lag behind hunter‐gatherers and high‐intensity agriculturalists. More datasets are needed to further elucidate the association between postcranial fracture risk and subsistence‐specific practices and environments within the Eurasian Steppe, where pastoralism has been the predominant form of economic activity for millennia.

“…Sometimes the callus is visible, but the fracture line itself cannot be seen (Devas & Sweetnam, 1956). The differential diagnosis for a stress fracture in skeletal samples may include neoplasm, infection, and sclerotic bone lesions of non‐infectious and non‐neoplastic origin (Gulati et al, 2021).…”

Section: Discussionmentioning

confidence: 99%

The hazards of the pastoralist lifestyle: Evidence from postcranial fractures in Middle Bronze and Early Iron Age populations of the Forest‐Steppe Altai, Russia

Tur,

Svyatko,

Rykun

et al. 2024

Intl J of Osteoarchaeology

View full text Add to dashboard Cite

A global comparison has shown that subsistence‐specific practices influenced the risk of postcranial fractures in prehistoric hunter‐gatherers and agriculturalists. Much less is known about pastoralists in this regard. The aim of the study was to investigate the prevalence and patterns of postcranial injuries of herders in the Forest‐Steppe Altai, Russia. Skeletal samples associated with the Andronovo Culture of the Middle Bronze Age, and Staroaleyka and Kamen Cultures of the Early Iron Age were studied. Long bones of 595 adults were examined for evidence of antemortem and perimortem injuries. Fracture frequencies were calculated per individual and per skeletal element, and the differences were evaluated statistically. While assessing per individual, the relative risk with a 95% confidence interval was calculated as well. All of the observed fractures were healed. This study suggests that pastoralists sustained not only traumatic, but also stress injuries. There were sex‐related differences in the rates, patterns, and location of the injuries. In the males, the main reason of fractures could have been high‐velocity incidents during horseback riding and using horse‐drawn vehicles. In the females, the majority of the injuries were possibly associated with accidents when walking (short falls and twists of ankle) and milking. Females of the Staroaleyka Culture sustained fractures of the limb bones significantly more often than those of the Kamen Culture, probably as a result of differences in their daily activities. In terms of the total fracture rates, the Forest‐Steppe Altai pastoralists and their neighbors seem to have surpassed low‐intensity agriculturalists but lag behind hunter‐gatherers and high‐intensity agriculturalists. More datasets are needed to further elucidate the association between postcranial fracture risk and subsistence‐specific practices and environments within the Eurasian Steppe, where pastoralism has been the predominant form of economic activity for millennia.

“…We considered bone sclerosis and cortical thickening as two specific bone alterations associated with CO. Bone sclerosis is a considerable alteration in the diagnosis of CO; however, this finding may be present in various congenital, autoimmune, and other rare diseases [ 16 ]. Similarly, cortical thickening, the second-most prevalent radiographic sign of CO, is subject to interpretation.…”

Section: Discussionmentioning

confidence: 99%

Prevalence of radiographic findings in chronic osteomyelitis

Tuon,

Mendonça,

Gasperin

et al. 2024

BMC Musculoskelet Disord

View full text Add to dashboard Cite

Background Simple radiography in conjunction with pertinent medical history and a comprehensive physical examination is typically adequate for diagnosing chronic osteomyelitis (CO). However, radiographic manifestations of CO lack specificity; therefore, the concordance among specialists in this regard has not been systematically assessed. This study aimed to compare and evaluate the proficiency of orthopedic surgeons and radiologists in identifying radiographic indicators present in simple radiographs for diagnosing CO. Methods This cross-sectional study was a correlational investigation utilizing plain radiographs obtained from a cohort of 60 patients diagnosed with CO. Comprehensive assessments of the demographic and clinical characteristics, comorbidities, and microbiological parameters were conducted. Additional variables included the anatomical location of the CO, existence of fistulas, disease duration, and presence of pseudoarthrosis. This study meticulously documented the presence or absence of six specific findings: bone destruction, which incorporates erosion and radiolucencies around implants; bone sclerosis; cortical thinning concomitant with erosion; cortical thickening; sequestrum formation; and soft-tissue swelling. Results Most patients were men (75%), with a mean age of 45.1 years. Hematogenous etiology of CO represented 23%. Bone sclerosis (71.3%) and cortical thickening (67.7%) were the most common radiographic findings, followed by soft-tissue swelling (51.3%), sequestration (47.3%), bone destruction (33.3%), and cortical erosion (30.3%). The mean agreement was 74.2%, showing a marked disagreement rate of 25.8% among all radiographic findings. The presence or absence of soft tissue edema, a prominent radiographic finding that was more important than the other findings, showed the greatest disagreement. Conclusions Radiographic findings in CO were universally observed in all patients, demonstrating a high degree of concordance among specialists, with the exception of soft tissue swelling.

“…Diffuse sclerosis of bone matrix can be caused by congenital and developmental disorders (eg, osteopetrosis, sclerosteosis, osteopoikilosis, Camurati-Engelmann disease), depositional disorders (eg, Gaucher disease, mastocytosis), metabolic disorders (eg, renal osteodystrophy, fluorosis, hypervitaminosis D), multiple myeloma, myeloproliferative disease, myelofibrosis, and also diffuse skeletal metastases as in our patient. 1,2 Most common primary malignancies causing diffuse bone involvement are breast and prostate cancer and lymphomas. 2 Bone metastasis is rare in gastric cancer patients.…”

mentioning

confidence: 99%

Intense 68Ga-DOTA-FAPI-04 Uptake in Diffuse Sclerotic Skeletal Metastases of Gastric Cancer

¹

,

²

,

³

et al. 2022

Clin Nucl Med

View full text Add to dashboard Cite

Diffuse sclerotic metastases of the bone as initial presentation at gastric carcinoma are very rare. We present a 48-year-old man who was examined for pancytopenia and diagnosed with gastric cancer. 18 F-FDG PET/CT showed moderate uptake in the primary gastric tumor and mild uptake in diffuse sclerotic metastatic lesions in the bone matrix, whereas 68 Ga-DOTA-FAPI-04 showed mild uptake in the gastric lesion and intense uptake at the whole skeleton.

scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

Contact Info

hi@scite.ai

10624 S. Eastern Ave., Ste. A-614

Henderson, NV 89052, USA

Product

Browser Extension Assistant by scite Citation Statement Search Reference Check Visualizations Dashboards Explore Journals Explore Organizations Explore Funders Embedding Badge Embedding Citation Search Pricing

Resources

Blog Help & FAQ Accessibility Statement API Terms For Universities & Governments For Researchers For Publishers For Corporate, Pharma & Enterprise Author Marketing Become an Affiliate Get an organization trial or quote scite Data & Services

About

News & Press Careers Read our Paper Coverage

Blog Terms and Conditions API Terms Privacy Policy Contact Cookie Preferences Do Not Sell or Share My Personal Information

Copyright © 2024 scite LLC. All rights reserved.

Made with 💙 for researchers

Part of the Research Solutions Family.