Sclerosing Bone Disorders

Hepatitis C-associated Osteosclerosis: A New Case with Long-term Follow-up and a Review of the Literature

“…In addition, the above disorders were excluded based on the findings of appropriate investigations, and a physical examination showed no evidence of neoplastic, granulomatous or hematological disorders associated with osteosclerosis. Primary hyperparathyroidism may cause osteosclerosis (19), and our patient's serum parathyroid hormone (PTH) level was elevated, but only in the presence of a repeatedly normal calcium level. Furthermore, a full blood count, measurements of the serum creatinine, fluoride and vitamin A levels and urinary heavy metal screening tests were normal, and the patient's normal serum 25-hydroxy vitamin D level excluded a diagnosis of excess vitamin D ingestion.…”

Hepatitis C-associated Osteosclerosis: A New Case with Long-term Follow-up and a Review of the Literature

“…In addition, the above disorders were excluded based on the findings of appropriate investigations, and a physical examination showed no evidence of neoplastic, granulomatous or hematological disorders associated with osteosclerosis. Primary hyperparathyroidism may cause osteosclerosis (19), and our patient's serum parathyroid hormone (PTH) level was elevated, but only in the presence of a repeatedly normal calcium level. Furthermore, a full blood count, measurements of the serum creatinine, fluoride and vitamin A levels and urinary heavy metal screening tests were normal, and the patient's normal serum 25-hydroxy vitamin D level excluded a diagnosis of excess vitamin D ingestion.…”

Hypercalcemia due to CYP24A1 variants in five unrelated patients: diagnostic and clinical considerations

“… 10 Finally, we do not know if the pathogenic ALPL variation in patient 4 could have modified his clinical presentation as hypophosphatasia may be associated with hypercalcemia and hypercalciuria. 11 However, this is not typically seen in carriers or adult-onset disease. The patient did not have clinical evidence of hypophosphatasia and the serum total alkaline phosphatase was normal.…”

Treatment Approach for Knee Osteoarthritis with Ipsilateral Femoral Cartilage Tumor: A Case Series

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Hepatitis C-associated Osteosclerosis: A New Case with Long-term Follow-up and a Review of the Literature

“…In addition, the above disorders were excluded based on the findings of appropriate investigations, and a physical examination showed no evidence of neoplastic, granulomatous or hematological disorders associated with osteosclerosis. Primary hyperparathyroidism may cause osteosclerosis (19), and our patient's serum parathyroid hormone (PTH) level was elevated, but only in the presence of a repeatedly normal calcium level. Furthermore, a full blood count, measurements of the serum creatinine, fluoride and vitamin A levels and urinary heavy metal screening tests were normal, and the patient's normal serum 25-hydroxy vitamin D level excluded a diagnosis of excess vitamin D ingestion.…”

Hypercalcemia due to CYP24A1 variants in five unrelated patients: diagnostic and clinical considerations

“… 10 Finally, we do not know if the pathogenic ALPL variation in patient 4 could have modified his clinical presentation as hypophosphatasia may be associated with hypercalcemia and hypercalciuria. 11 However, this is not typically seen in carriers or adult-onset disease. The patient did not have clinical evidence of hypophosphatasia and the serum total alkaline phosphatase was normal.…”

Treatment Approach for Knee Osteoarthritis with Ipsilateral Femoral Cartilage Tumor: A Case Series

“……”

Hepatitis C-associated Osteosclerosis: A New Case with Long-term Follow-up and a Review of the Literature

“…In addition, the above disorders were excluded based on the findings of appropriate investigations, and a physical examination showed no evidence of neoplastic, granulomatous or hematological disorders associated with osteosclerosis. Primary hyperparathyroidism may cause osteosclerosis (19), and our patient's serum parathyroid hormone (PTH) level was elevated, but only in the presence of a repeatedly normal calcium level. Furthermore, a full blood count, measurements of the serum creatinine, fluoride and vitamin A levels and urinary heavy metal screening tests were normal, and the patient's normal serum 25-hydroxy vitamin D level excluded a diagnosis of excess vitamin D ingestion.…”

Hypercalcemia due to CYP24A1 variants in five unrelated patients: diagnostic and clinical considerations

“… 10 Finally, we do not know if the pathogenic ALPL variation in patient 4 could have modified his clinical presentation as hypophosphatasia may be associated with hypercalcemia and hypercalciuria. 11 However, this is not typically seen in carriers or adult-onset disease. The patient did not have clinical evidence of hypophosphatasia and the serum total alkaline phosphatase was normal.…”

Treatment Approach for Knee Osteoarthritis with Ipsilateral Femoral Cartilage Tumor: A Case Series

“……”