Schistosomal Myelopathy in Childhood: Findings of Magnetic Resonance Imaging in 26 Patients

Henriques-Souza, Adélia Maria de Miranda; Valênça, Marcelo Moraes

doi:10.1016/j.pediatrneurol.2011.09.006

Cited by 11 publications

(10 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2 The laboratory tests of CSF reveal nonspecific findings. 1,4 Our patient presented normal protein and glucose levels; pleocytosis was not evidenced.…”

Section: Discussionmentioning

confidence: 61%

“…However, strong evidences indicate it is an underdiagnosed condition. 1,4 The typical patient of this disease is young, male, presenting low back or lower limbs pain, usually of radicular pattern, followed by weakness and progressive sensorial loss in the lower limbs, associated with autonomic dysfunction, mainly of the bladder. 1 The diagnosis is primarily based on clinical examination.…”

Section: Discussionmentioning

confidence: 99%

“…Around 26 million Brazilians are at risk of contracting it. 4 The typical manifestations of schistosomiasis include the urogenital, gastrointestinal and hepatolienal systems. The central nervous system involvement by S. mansoni is an atypical presentation, occurring by anomalous migration of the schistosome or unusual egg deposition from the portal venous system, through the venous plexus of Batson.…”

Section: Introductionmentioning

confidence: 99%

“…The central nervous system involvement by S. mansoni is an atypical presentation, occurring by anomalous migration of the schistosome or unusual egg deposition from the portal venous system, through the venous plexus of Batson. 3,4 This explains the higher prevalence of conus medullaris and thoracolumbar medulla envelopment. The involvement of the cervical spinal cord is rare, with few cases being reported in literature.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Schistosomal Cervical Myelopathy

Farias

Mendes

et al. 2018

Arq Bras Neurocir

View full text Add to dashboard Cite

Schistosomiasis is an infectious disease caused by trematode platyhelminths of the genus Schistosoma. The involvement of the cervical spinal cord is rare, with few cases reported in the literature. The management of such patients is particularly challenging, since clinical and radiological findings may be confounded with other inflammatory diseases and/ or spinal cord tumors. We describe a 20-year old male with a history of swimming outdoors. He first presented pain in the back of the neck extending to shoulders and upper limbs paresis associated with four limbs hyperreflexia. The magnetic resonance imaging (MRI) showed a hypointense T1-weighted lesion in the cervical spinal cord, which was hyperintense on T2 images. The serologic testing was negative for schistosomiasis. A cervical cord biopsy at the C5-C6 level showed Schistosoma eggs in the histopathological examination. The treatment was performed using a single dose of praziquantel 50 mg/kg, with prednisone 40 mg/day for 3 weeks. On the follow-up, 1 year later, the patient presented mild reduction of the vibratory sensitivity in the distal third of both legs. Our illustrative case strengthens that, in endemic regions, Schistosoma mansoni infestation should be included in the differential diagnosis of intramedullary expansive lesions.

show abstract

“…2 The laboratory tests of CSF reveal nonspecific findings. 1,4 Our patient presented normal protein and glucose levels; pleocytosis was not evidenced.…”

Section: Discussionmentioning

confidence: 61%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Schistosomal Cervical Myelopathy

Farias

Mendes

et al. 2018

Arq Bras Neurocir

View full text Add to dashboard Cite

show abstract

“…Mycoplasma pneumonia may also cause myelitis, although this may represent a parainfectious mechanism without direct infection of the cord [4,34]. Granulomatous disease (primarily tuberculosis and rarely sarcoidosis [39]) and parasitic infections (such as Schistosoma mansoni [40] and neurocysticercosis [41]) can affect the spinal cord as well. We illustrate a child with urosepsis and bacterial myelitis (Fig.…”

Section: Other Infectionsmentioning

confidence: 99%

Longitudinally extensive myelopathy in children

et al. 2015

View full text Add to dashboard Cite

When children present with acute myelopathy manifested by sensory, motor, or bowel and bladder symptoms, MRI of the neuraxis with contrast agent is the most important imaging study to obtain. Although occasionally normal, MRI often demonstrates signal abnormality within the spinal cord. Classically, longitudinally extensive transverse myelitis (≥3 vertebral bodies in length) has been described with neuromyelitis optica (NMO), but alternative diagnoses should be considered. This pictorial essay reviews the differential diagnoses that may present with longitudinally extensive spinal cord signal abnormalities. Multiple inflammatory, infectious, vascular, metabolic and neurodegenerative etiologies can present with a myelopathy. Thus, radiologists can assist in the diagnosis by familiarizing themselves with the spectrum of diseases in childhood that result in longitudinally extensive signal abnormalities in the absence of trauma.

show abstract

Infections of the Spinal Cord

Carod-Artal

2014

CNS Infections

View full text Add to dashboard Cite

Schistosomal Myelopathy in Childhood: Findings of Magnetic Resonance Imaging in 26 Patients

Cited by 11 publications

References 8 publications

Schistosomal Cervical Myelopathy

Schistosomal Cervical Myelopathy

Longitudinally extensive myelopathy in children

Infections of the Spinal Cord

Contact Info

Product

Resources

About